Comparison of the effectiveness of Gastal and Rennie
The effectiveness of Gastal is quite similar to Rennew - this means that the ability of the medicinal substance to provide the maximum possible effect is similar.
For example, if the therapeutic effect of Gastal is more pronounced, then using Rennie, even in large doses, will not achieve this effect.
Also, the speed of therapy - an indicator of the speed of therapeutic action - is approximately the same in Gastal and Rennie. And bioavailability, that is, the amount of a drug reaching its site of action in the body, is similar. The higher the bioavailability, the less it will be lost during absorption and use by the body.
Comparison of the effectiveness of Rennie and Almageli A
The effectiveness of Rennie is quite similar to Almagel A - this means that the ability of the drug substance to provide the maximum possible effect is similar.
For example, if the therapeutic effect of Rennie is more pronounced, then using Almagel A even in large doses will not achieve this effect.
Also, the speed of therapy is an indicator of the speed of therapeutic action in Rennie and Almageli A are approximately the same. And bioavailability, that is, the amount of a drug reaching its site of action in the body, is similar. The higher the bioavailability, the less it will be lost during absorption and use by the body.
Comparison of Gastal and Rennie safety
The safety of a drug includes many factors.
Moreover, Gastal’s is higher than Rennie’s. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing metabolism in Gastal, as well as in Rennie, we look at which organ is the metabolizing organ and how critical the effect on it is.
The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Gastal has fewer risks when used than Rennie.
Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using Gastal and Rennie.
Comparison of safety of Rennie and Almageli A
The safety of a drug includes many factors.
At the same time, for Almageli A it is higher than for Rennie. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing metabolism in Almageli A, as well as in Rennie, we look at which organ is the metabolizing one and how critical the effect on it is.
The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Almagel A has fewer risks when used than Rennie.
Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using Almageli A and Rennie.
Comparison of habituation in Gastal and Rennie
Like safety, addiction also involves many factors that must be considered when evaluating a drug.
Thus, the totality of the values of such parameters as “syndrome” in Gastal is quite similar to the similar values in Rennie. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body. And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible. At the same time, in Gastal the meaning of the “syndrome” is quite small, however, just like in Rennie.
Comparison of habituation in Rennie and Almageli A
Like safety, addiction also involves many factors that must be considered when evaluating a drug.
So, the totality of the values of such parameters as “Rennie’s syndrome” is quite similar to the similar values of Almagel A. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body. And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible. At the same time, Rennie’s “syndrome” values are quite small, however, the same as for Almageli A.
Comparison of side effects of Gastal and Rennie
Side effects or adverse events are any adverse medical event that occurs in a subject after administration of a drug.
Gastal's adverse event status is almost the same as Rennie's. They both have few side effects. This implies that the frequency of their occurrence is low, that is, the indicator of how many cases of an undesirable effect of treatment are possible and registered is low. The undesirable effect on the body, the strength of influence and the toxic effect of Gastal are similar to Rennew: how quickly the body recovers after taking it and whether it recovers at all.
Comparison of side effects of Rennie and Almageli A
Side effects or adverse events are any adverse medical event that occurs in a subject after administration of a drug.
Rennie's level of adverse events is almost the same as that of Almagel A. Both of them have a small number of side effects. This implies that the frequency of their occurrence is low, that is, the indicator of how many cases of an undesirable effect of treatment are possible and registered is low. The undesirable effect on the body, the strength of influence and the toxic effect of Rennie are similar to Almagel A: how quickly the body recovers after taking it and whether it recovers at all.
Comparison of addiction between Gastal and Phosphalugel
Like safety, addiction also involves many factors that must be considered when evaluating a drug.
Thus, the totality of the values of such parameters as “o syndrome” in Gastal is quite similar to the similar values in Phosphalugel. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body. And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible. At the same time, in Gastal the meaning of the “syndrome” is quite small, however, the same as in Phosphalugel.
Answers on questions
Yuri Aleksandrovich Kucheryavy answers questions from viewers of the conference “Gastrointestinal Motility: Past, Present, Future.”
Can a therapist (based on the patient’s complaints) determine hyper- or hypomotility of the gastrointestinal tract?
Olga Andreevna answered this question. Once again - pain behind the sternum of a compressive nature, a feeling of a lump behind the sternum, especially in combination with heartburn and/or acid regurgitation - signs of hypermotility of the esophagus. Severe distension in the epigastrium after eating (posttrandial distress syndrome) are signs of gastric hypomotility. These are obvious signs. They can be combined. In any case, the administration of ganaton to most patients with such symptoms will lead to improvement - in the first case, due to the reduction of gastroesophageal reflux, secondary spastic (very conditionally they can be called compensatory) dyskinesia of the esophagus will decrease. In the second case, there is a direct pathogenetic effect - improved evacuation and resolution of symptoms.
Kaliningrad. Chekhovskikh Anna Valerievna And what is the differential diagnosis of cardiac complaints - the symptoms are similar to unstable angina, CHF should also be excluded - I mean the horizontal position.
It's a difficult question. Most patients, due to the greater emphasis on the attention of both doctors and “reading” citizens, first of all come under the care of cardiologists, and only after undergoing examinations excluding coronary artery disease, patients undergo endoscopy and go to a gastroenterologist. For an experienced cardiologist and gastroenterologist, it will not be difficult to make a differential diagnosis between diseases of the esophagus and the cardiovascular system already at the stage of physical examination. For a practicing physician, we can recommend that all patients undergo an ECG as a simple, accessible and non-invasive test. Any doubts about the validity of the diagnosis of coronary artery disease should be interpreted in favor of prescribing a consultation with a gastroenterologist and/or endoscopy. It must be remembered that often patients with GERD with chest pain, especially the elderly, may have abnormalities on the ECG, including those coinciding with chest pain. This also should not stop the physician from continuing to look for GERD in a patient with seemingly obvious CAD.
How do you feel about the drugs Gastal, Rennie for heartburn? More often, doctors prescribe them once.
The place of these drugs is only for symptomatic use for functional heartburn or as an on-demand drug when symptoms of GERD occur during pathogenetic treatment (PPI +/- ganaton)
Pimenov, Kaluga Manifestation of dyspeptic symptoms over the age of 40–45 years - what is your advice on differential diagnosis.
Look for organics. You'll probably find it
If patients rarely experience heartburn after eating, what is the best drug to prescribe and for how long?
Heartburn—once a week or more—highly suggests a diagnosis of GERD; if less often, the diagnosis of GERD is questionable, but requires clarification.
Arkhangelsk. Slipchenko Oksana Val What is the proportion of the combination of GERD and IBS
About 20%
Are enzyme preparations used for GERD? Can you explain please.
Should not be used unless there are specific indications for this, for example, concomitant pancreatitis with exocrine insufficiency.
What foods aggravate GERD?
Food that stays in the stomach for a long time - any dense food, fatty, floury, especially fresh baked goods; foods that provoke and aggravate motor dysfunction - chocolate, nuts, coffee, carbonated drinks; food has a locally irritating and juice-like effect, increasing hypersecretion in the stomach.
Arkhangelsk What is the place of PPI monotherapy in patients with GERD? When to prescribe combination therapy?
PPI therapy is prescribed to everyone and always (if there is reflux esophagitis and stomach), ganaton is added to everyone for 8 weeks, because This is a pathogenetic treatment. If a PPI is not prescribed, it is a grave mistake. For all patients with clinically significant motor impairment, with a combination of functional dyspepsia and GERD, failure to prescribe Ganaton would also be a serious tactical mistake.
N. Novgorod. 1. The condition after surgery on the esophagus or stomach requires constant use of ganaton. How long?
If you managed to achieve positive dynamics with the help of ganaton, it will last for a very long time, perhaps even for life.
2. Patients with visceroptosis and decreased tone of the gastrointestinal sphincters: What is the role of ganaton and for how long?
There is no such indication in the instructions. This is an experimental purpose based on theoretical premises. The effect is quite possible.
Comparison of the safety of Gastal and Phosphalugel
The safety of a drug includes many factors.
At the same time, in Gastal it is quite similar to Phosphalugel. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing metabolism in Gastal, as well as in Phosphalugel, we look at which organ is the metabolizing organ and how critical the effect on it is.
The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Gastal does not have any risks when used, just like Phosphalugel.
Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using Gastal and Phosphalugel.
Comparison of the effectiveness of Gastal and Phosphalugel
The effectiveness of Gastal is quite similar to Phosphalugel - this means that the ability of the drug substance to provide the maximum possible effect is similar.
For example, if the therapeutic effect of Gastal is more pronounced, then using Phosphalugel even in large doses will not achieve this effect.
Also, the speed of therapy is an indicator of the speed of therapeutic action; Gastal and Phosphalugel are approximately the same. And bioavailability, that is, the amount of a drug reaching its site of action in the body, is similar. The higher the bioavailability, the less it will be lost during absorption and use by the body.
Comparison of side effects of Gastal and Phosphalugel
Side effects or adverse events are any adverse medical event that occurs in a subject after administration of a drug.
Gastal's side effects are almost the same as those of Phosphalugel. They both have few side effects. This implies that the frequency of their occurrence is low, that is, the indicator of how many cases of an undesirable effect of treatment are possible and registered is low. The undesirable effect on the body, the strength of influence and the toxic effect of Gastal are similar to Phosphalugel: how quickly the body recovers after taking it and whether it recovers at all.
