Ultop or Omeprazole: which is better and what is the difference, patient reviews

Living in big cities, predominantly sedentary work, non-compliance with the daily routine and nutrition directly affect the functioning of the entire digestive tract. In addition, constant stress and taking medications, especially non-steroidal anti-inflammatory drugs, are the cause of unpleasant diseases, which tend to become chronic in the absence of proper therapy. Ultimately, this can lead to disastrous consequences, which can only be eliminated through surgery.

If regular problems with the functioning of the stomach and intestines occur, the symptoms cannot be ignored. The following symptoms are alarming:

• Feeling of fullness immediately after starting to eat;
• Heartburn;
• Sour belching;
• Dry mouth and throat;
• Heaviness in the stomach associated with a failure of its normal functioning;
• Nausea and desire to “empty” the stomach;
• Pain in the upper abdomen, often radiating to the left side of the chest and between the shoulder blades;
• Profuse diarrhea or frequent half-formed stools;
• shortness of breath or coughing;
• White coating on the tongue.

When such manifestations occur frequently or even have a regular character, this may indicate the development of gastric dyspepsia, gastric ulcer or duodenal ulcer, gastroesophageal reflux disease, as well as Zollinger-Ellison syndrome.

Any of these diagnoses can significantly reduce a person’s quality of life, force him to give up his favorite sport and go on a constant diet. To prevent such an outcome, you must immediately seek qualified medical help.

During drug therapy, drugs such as Ultop or Omeprazole are prescribed.

Composition of the drug Ultop and its therapeutic effects

The drug Ultop is a gelatin capsule with enteric granules of the active substance omeprazole in different dosages and packaging:

Ultop 10 mg, 14 capsules

1. A cardboard pack containing 2-4 blisters containing 7 Ultop capsules with 10, 20, 40 mg of active substance;
2. A cardboard box containing 1 polymer bottle containing 14 or 28 Ultop capsules with 10, 20, 40 mg of active substance.

In addition to the active substance omeprazole, each capsule also contains auxiliary ingredients:

• Sucrose;
• Corn starch;
• Talc;
• Sodium lauryl sulfate;
• Hydroxypropylcellulose;
• Magnesium carbonate is heavy;
• Methacrylate copolymer dispersion;
• Macrogol 6000;
• Titanium dioxide (E171);
• Gelatin;
• Iron oxide red (E172).

Ultop is also available in powder form for the preparation of a solution for injection. The cardboard package contains 1 ampoule with powder containing 40 mg of active substance.

The drug Ultop is prescribed to patients to reduce the production of gastric juice. The active substance included in its composition, entering the stomach, binds directly to enzymes produced by the cells of the stomach walls and reduces their activity.

Ultop capsules begin their full effect on the body within an hour after the first oral administration. This dynamic will last 70 hours. If the patient takes the drug repeatedly, its positive effect lasts up to 4 days. Relief of symptoms occurs immediately after the first dose.

Upon completion of therapy with the drug Ultop, its complete removal from the body will occur within 3-5 days. In patients suffering from liver failure, this process takes up to 7 days.

Similarities of drugs

These drugs can be called complete analogues. Both Omeprazole and Ultop are based on one active ingredient - omeprazole. They are just sold under different trade names.

Accordingly, they are dispensed in the same dosage forms - in capsules and in solution for intravenous administration. Their side effects are the same and appear with the same strength.

Advantages and disadvantages

The advantage of this drug is that patients with liver failure can take it and such therapy will be successful. In addition, in addition to capsules for oral use, Ultop is available in powder form for injection. This form is available without a prescription.

The disadvantages of Ultop are that it has contraindications for interaction with many drugs. Taking this medication increases the risk of intestinal infections due to decreased production of gastric juice. During pregnancy, Ultop is taken after assessing all the risks for the mother and child, and under the supervision of a doctor. When breastfeeding a child, therapy for his mother with this medicine is prohibited. Ultop reduces concentration and slows down psychomotor reactions, so people with responsible positions in production should not take this drug while working. An overdose of this drug is also possible, so it should be taken strictly as prescribed by your doctor. Ultop is more expensive than its analogues.

Special instructions for the use of these medications

Since these drugs are used to treat peptic ulcers, antibacterial drugs are also prescribed in parallel with taking these drugs.

But before prescribing such medications, a person must undergo tests to refute malignant neoplasms in the gastric tract. This is a mandatory and necessary measure.

"Omeprazole" is able to mask early signs of cancer and thus make it difficult to timely detect such a dangerous defect. It is also necessary to determine how the liver and kidneys function.

Patient reviews

Natalya: “Back in my student years, I developed gastritis and during this time I tried all sorts of medications for it.
It all came to the point that no pills could relieve heartburn and pain. The doctor I contacted recommended Ultop to me. Relief came after the first dose, and repeated stomach problems became much less frequent.” Ruslan: “I took these capsules for a month. In moments of exacerbation, he even swallowed two at a time. I didn’t feel any particular difference from cheap analogues”

Analogs of these medicines

First of all, analogues cannot be selected and determined without consulting a specialist. And if there is a need for replacement, then you should contact your doctor about this issue.

At the moment, the most common analogues of such drugs are:

• "Omez."

• "Nolpaza".

• "Gastrozol".

• "Pariet."

It is worth noting that the above medications are only a small part of the analogues presented on a specific market. But at the same time, every person should understand that choosing a replacement drug on their own is a rather stupid and dangerous undertaking. Therefore, if it is not possible to purchase the necessary drug, then you should consult a specialist about a replacement.

It is important to remember: independent decision-making in such cases is unacceptable and even dangerous. After all, a peptic ulcer can lead to disastrous complications, so take care of yourself and your own health.

Therapeutic effects of the drug Omeprazole and its composition

Omeprazole is prescribed to patients with ulcerative lesions of the stomach and duodenum, as well as Zollinger-Ellison syndrome. Immediately after the first dose of the drug with a dosage of 20 mg, the patient disappears from all painful manifestations. This dynamic will last 17 hours. This happens because the active substance omeprazole inhibits the functioning of the stomach cells responsible for the secretion of gastric juice. When you take the substance again, the cumulative therapeutic process will begin. Omeprazole is removed from the body through the kidneys and bile within 4 days.

The release form of the drug Omeprazole has all possible convenient expressions:

1. A cardboard pack containing blisters containing 10, 14, 20, 28, 30, 100 capsules of Omeprazole with 20, 40 mg of active substance;
2. Cardboard pack with blisters containing 7, 14 film-coated Omeprazole tablets with 10 mg of active substance;
3. A cardboard box containing 5 bottles of powder for the preparation of a solution for injection with 40 mg of the active substance omeprazole in each.

   
   Omeprazole 20 mg, 30 capsules

In addition to the main active substance omeprazole, the medicine contains the following auxiliary ingredients:

• Sucrose;
• Lactose;
• Mannitol,
• Disodium hydroorthophosphate,
• Calcium carbonate,
• Sodium lauryl sulfate,
• Hydroxypropyl methylcellulose,
• Methacrylic acid L30D,
• Polysorbate 80,
• Sodium hydroxide,
• Propylene glycol,
• Titanium dioxide (E 171),
• Povidone S-630,
• Lactose,
• Cetyl alcohol.
• Propyl parahydroxybenzoate,
• Methyl parahydroxybenzoate,
• Titanium dioxide (E 171),
• Gelatin.

Omeprazole

The drug is in the form of capsules that contain 20 and 40 mg of the active ingredient. Also available in the form of a solution for intravenous drip. The active ingredient is omeprazole. This means that both drugs are based on the same active ingredient.

Medicinal properties

The drug Omeprazole acts by the same mechanism as Ultop. It blocks H+-ATPase, thereby reducing the production of hydrochloric acid to a minimum. The effect does not depend on the factor that stimulates secretion, but depends on the dosage of the drug. One dose can last up to two days.

The duration of action immediately after administration is similar. Within a week after the end of treatment, the function of releasing hydrochloric acid is completely restored. But before this, erosive and ulcerative lesions of the mucous membranes have already healed. This takes from two to eight weeks. The duration of treatment depends on the stage of the disease and the location of the erosion.

Indications and contraindications

Omeprazole is indicated for adults with the following diseases:

• upper intestinal ulcer
• benign gastric ulcer and prevention;
• preventing ulcer recurrences;
• eradication of Helicobacter peptic ulcer;
• stomach protection when taking NSAIDs;
• treatment of reflux esophagitis.

It is also prescribed to eliminate the symptoms of gastritis, reflux esophagitis, and ulcerative-erosive lesions.

The use of Omeprazole is contraindicated in cases of high sensitivity to the active ingredients or substituted benzimidazoles. Cannot be taken during concurrent treatment with atazanavir or nelfinavir.

Adverse reactions

Due to the fact that Omeprazole contains the same active ingredient as Ultop, its safety profile is similar. Adverse reactions are completely the same and also do not require treatment or discontinuation of the drug, unless it is an allergy. In other cases, you need to consult a doctor.

Features of treatment

You should immediately consult a doctor if you notice symptoms such as:

• weight loss for no apparent reason;
• periodic vomiting;
• vomiting blood or foam;
• sharp pain in the abdomen.

If the doctor suspects the presence of an ulcer or the disease has already been diagnosed, malignant processes should be excluded. This is because both drugs can mask the symptoms of a stomach tumor.

Medicines contain lactose and sucrose. This should be taken into account in case of intolerance to these substances and/or impaired absorption. During therapy, the risk of infection with salmonella and campylobacter may increase. If long-term treatment is required, you need to carefully monitor the patient's condition: blood count, kidney and liver function, condition of the stomach and intestines.

Advantages and disadvantages

The advantages of the drug Omeprazole are due to the fact that patients immediately feel an improvement in their condition and this effect lasts for a day. The big advantage is the different release form. After all, there are those who have difficulty swallowing capsules. Omeprazole can be taken not only during complex therapy, but also in acute conditions. The drug costs less than its analogues.

The disadvantage of the drug is that it should not be used during pregnancy, lactation and breastfeeding, as well as in the presence of liver disease.

Differences

Despite the large number of similarities and similar effects, Ultop still differs from Omeprazole.

Manufacturer

First of all, the drugs are manufactured by different companies. Russian pharmacies sell not only domestic Omeprazole, but also a drug with the same name from companies in other countries. You can find Omeprazole on sale from the following manufacturers:

• Nizhpharm;
• Teva;
• Obolenskoye FP;
• Gideon Richter;
• Canonpharma.

Ultop is produced by KRKA in Slovenia. The drug with this trade name is not produced anywhere else.

Price

Omeprazole in Moscow pharmacies costs from 54 to 156 rubles per package, depending on the number of capsules and their dosage. Ultop price ranges from 120 to 474 rubles per package. This is another difference between Ultop and Omeprazole. You can buy the drugs with a prescription from a gastroenterologist.

Safety

The instructions for Omeprazole indicate that it can be prescribed to a child over one year old or with a body weight of more than ten kilograms. In pediatrics, Omeprazole is prescribed to children with reflux esophagitis. A child over four years old – with an ulcer due to infection with Helicobacter.

The manufacturer in the annotation for Ultop indicates that treatment is possible only from the age of twelve. This suggests that adequate safety testing of the drug has not been conducted in this age group. According to reviews, children are more often prescribed Omeprazole.

Therefore, the difference between Omeprazole and Ultop is also that the first can be prescribed to a child - for treatment, alleviation of symptoms or prevention of the disease.

Before starting treatment, when choosing a drug, you must consult a gastroenterologist. Only a specialist can take into account the individual characteristics of the course of the disease in order to select the most optimal drug and its dosage.

Ultop and Omeprazole - comparison table

Omez: basic properties

An antiulcer drug, the therapeutic effect of which is due to the manifestation of the specific properties of the main component - omeprazole (a proton pump inhibitor substance). Under its influence, the synthesis of hydrochloric acid is blocked. As a result of this effect, a decrease in both basal and stimulated secretion is observed.

The therapeutic effect will appear after 1 hour from the moment of application of the drug.

According to the instructions for Omez, it is prescribed for gastrointestinal ulcers, pancreatitis, erosive-ulcerative esophagitis, and systemic mastocytosis.

The release form of the medicine is capsules (10 mg, 20 mg, 40 mg), lyophilisate for the preparation of an injection solution.

The best medicine, according to experts

Which drug should you choose? According to experts, it is impossible to definitively answer which is better - Ultop or Omeprazole. Each case of gastrointestinal tract disease has its own specific dynamics and characteristics. In addition, doctors note that in 32% of cases, therapy using these drugs is not at all effective.

Omeprazole is attractive due to its lower price. Whereas Ultop is suitable for patients with liver failure. The difference in the cost of drugs is explained only by different production technologies and countries of manufacture.

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What do the experts say?

The vast majority of experts do not give any recommendations as to which drug is better. Each attending physician insists that medications are selected strictly individually and according to the patient’s medical history.

But still, some doctors shared their experience that sometimes patients are immune to the constituent substances of Omeprazole. In other words, after therapy with this drug, improvement did not occur.

Features of differences

There are no fundamental differences between the drugs “Omez” and “Ultop”. Both drugs have the same effect, are quite effective, and show good results in the treatment of peptic ulcers, gastritis with high acidity, and other hyperacid conditions.

The two main differences between the drugs are the price and quality of chemical cleaning

There is a slight difference in the composition of the excipients, which should be taken into account by people with individual intolerance to one or another component.

Information! Ultop has a high degree of purification, but this factor is only important when taking the medicine for a long time.

It also has an increased cost relative to Omez. This must be taken into account when prescribing therapy to low-income patients.