Nemozol - instructions for use, doses, side effects, contraindications, price, where to buy

Pharmacological properties of the drug Nemozol™

Pharmacodynamics. Albendazole is a broad-spectrum anthelmintic agent that is also active against pathogenic protozoa. Acts on intestinal and tissue forms of parasites; active against eggs, larvae and adult helminths. The antihelminthic effect of the drug is due to inhibition of tubulin polymerization, which leads to metabolic disturbances and death of the helminth. Albendazole is active against intestinal parasites, including nematodes (Ascaris lumbricoides, Triсhiurus triсhiura, Enterobius vermicularis, Ancylostoma duodenale, Necator americanus, Strongiloides stercoralis, Cutaneous Larva Migrans), cestodam (Hymenolepsis nana, Taenia solium, Taenia saginata), trematodes (Opisthorhis viverrini, Clonorchis sinensis), the simplest (Giardia lamblia (intestinalis and duodenalis). Albendazole is effective against tissue parasites, including cystic echinococcosis and alveolar echinococcosis, caused by invasion Echinococcus granulosus And Echinococcus multilocularis respectively. The drug is also effective in the treatment of neurocysticercosis caused by infestation of pork tapeworm larvae T.solium, capillariasis caused by invasion Gnatostoma spinigerum. Albendazole destroys cysts or significantly reduces their size in patients with granular hydatid cysts. Pharmacokinetics. After oral administration, the drug is poorly absorbed (up to 5%) from the gastrointestinal tract. Simultaneous use of fatty foods increases the absorption of the drug approximately 5 times. Albendazole is 70% bound to blood plasma proteins and is freely distributed in the body; determined in urine, bile, liver, cyst wall and cyst fluid, CSF. Albendazole sulfoxide is rapidly converted in the liver to albendazole sulfone (a secondary metabolite) and other oxidized products. The half-life of albendazole sulfoxide from blood plasma lasts 8–12 hours. Albendazole sulfoxide and other metabolites are excreted primarily in the bile, and only a small amount is excreted in the urine. Since the renal excretion of albendazole and its primary metabolite, albendazole sulfoxide, is insignificant, clearance in patients with impaired renal function does not change. In patients with biliary obstruction, systemic bioavailability may be increased and the half-life of albendazole sulfoxide may be prolonged.

General principles of treatment

A unified approach to treating infection has not been developed. The drugs used have quite a lot of side effects, and taking them on your own is unacceptable. Often prescribed medications no longer work on some types of Giardia.

It should also be taken into account that giardiasis is often accompanied by other infections, such as infection with Candida fungi, the Helicobacter pylori bacterium or helminths, which also require treatment.

The disease has unclear criteria for recovery and re-infection. In general, we can say that both diagnosis and therapy are quite difficult.

Use of the drug Nemozol™

Use internally during meals. The oral bioavailability of albendazole is increased if the drug is taken with a fatty meal. Adults and children over 2 years of age are prescribed:

for enterobiasis, hookworm, necatoriasis, ascariasis, trichinosis, 400 mg (1 tablet) or 20 ml of suspension once. When treating enterobiasis, it is recommended to carry out simultaneous treatment of all persons living together;
for strongyloidiasis and taeniasis - 400 mg (1 tablet) or 20 ml suspension 1 time per day for 3 days;
for toxocariasis - 400 mg (1 tablet) or 20 ml suspension 1 time per day for 10 days;
for mixed infestations caused by Opisthorchis viverrini and Clonorchis sinensis - 400 mg (1 tablet) 2 times a day for 3 days.

Children aged 2–12 years with giardiasis are prescribed 400 mg (1 tablet) or 20 ml of suspension once a day for 5 days. For cystic echinococcosis, patients weighing more than 60 kg are prescribed Nemozol at a dose of 400 mg (1 tablet) or 20 ml of suspension 2 times a day for 28 days. For patients weighing less than 60 kg, albendazole preparations are used in a daily dose of 15 mg/kg, divided equally, in 2 doses. The maximum daily dose is 800 mg. The course of treatment can be repeated after a 14-day break; if necessary, 3 courses of treatment can be carried out. For alveolar echinococcosis, patients weighing more than 60 kg are prescribed Nemozol at a dose of 400 mg (1 tablet) or 20 ml of suspension 2 times a day for 3 courses of 28 days with 14-day breaks between courses. For patients weighing less than 60 kg, albendazole preparations are used in a daily dose of 15 mg/kg, divided equally, in 2 doses. The maximum daily dose is 800 mg. For neurocysticercosis, patients weighing more than 60 kg Nemozol are prescribed at a dose of 400 mg (1 tablet) or 20 ml of suspension 2 times a day for 7–30 days, depending on the clinical effect. For patients weighing less than 60 kg, albendazole preparations are used in a daily dose of 15 mg/kg, divided equally, in 2 doses. The maximum daily dose is 800 mg. The course of treatment is 7–30 days, a second course can be carried out after a 14-day break. For cutaneous larva migrans syndrome, 400 mg (1 tablet) or 20 ml of suspension is prescribed once a day for 1–3 days.

Taking Nemozol: benefits and harms

Nemozol is taken according to the prescribed regimen, which indicates the exact dose and course of treatment with the drug. Any anthelmintic drug has advantages and disadvantages.

Nemozol, as the main remedy for helminths, is:

treatment of helminths at different stages of development (eggs, larvae, healthy individuals that lay eggs);
rapid treatment, the course of which does not exceed two weeks (therapy is selected individually, based on the course of the disease and the patient’s condition);
a prophylactic suitable for use by adults and children;
relieves acute symptoms of giardiasis from the first dose;
easy to use (several forms of the drug: tablets for adults and suspension for children);
non-toxic to the patient's body.

The disadvantages of the drug include possible side effects, like any other anthelmintic drug.

Headaches, nausea and vomiting are a consequence of improperly prescribed therapy. Allergic reactions occur against the background of a weakened immune system of a small patient.

Side effects of the drug Nemozol™

from the gastrointestinal tract: stomatitis, dry mouth, heartburn, nausea, vomiting, abdominal pain, flatulence, diarrhea, constipation; from the cardiovascular system: arterial hypertension; from the central and peripheral nervous system: insomnia or drowsiness, headache, dizziness, confusion, disorientation, hallucinations, convulsions, decreased visual acuity; from the hematopoietic system: leukopenia, thrombocytopenia, pancytopenia; from the skin and its appendages: alopecia; from the urinary system: impaired renal function, acute renal failure; allergic reactions: itching, urticaria, pemphigus, dermatitis, chills; laboratory indicators: increased activity of liver enzymes.

Recommendations after treatment

After recovery, an adult must add basic hygiene rules to his personal daily to-do list, which significantly increase personal infectious safety and prevent re-infection.

Take time to wash your hands when entering an enclosed space, after going to the restroom, and don’t forget about this before sitting down to eat.
At a minimum, boil the water, it is advisable to buy a filter for the house and use it all day. With small children in the house, iron children's clothes after washing.
As owners of pets, it is worth performing mandatory deworming for dogs and cats in veterinary hospitals.
Immunity is a protective natural barrier. This barrier should be supported from all sides, starting with the intake of minerals and vitamins, ending with the harmonious distribution of working time, rest and sleep.
At the end of each year, check for cases of relapse by taking tests.

No ideal medicines have been invented that work instantly with 100% results, with a complete absence of negative effects and are suitable for you. Based on the results of treatment, the drug chosen by the doctor reveals positive and negative properties. For five years, Nemozol has been on the list of drugs often used for parasitic infections.

This is an effective medicine with maximum potential, gentle effects on the human body, with a wide spectrum of action.

Special instructions for the use of Nemozol™

During use of the drug, it is necessary to monitor the activity of liver enzymes before the start of each treatment cycle. If the indicators exceed the upper limit of normal by more than 2 times, the use of Nemozol must be stopped until the indicators are completely normalized. It is necessary to monitor the number of leukocytes at the beginning and every 2 weeks of the 28-day cycle of drug use. The use of Nemozol for leukopenia can be continued if the degree of reduction is insignificant and the leukopenia does not progress. Patients with neurocysticercosis should receive appropriate therapy with steroids and anticonvulsants. Special security measures. In order to prevent the use of Nemozol in the early stages of an unknown pregnancy, women of childbearing age can begin taking the drug only after receiving a negative pregnancy test result or at the beginning of menstruation. During the treatment period, with breaks between courses inclusive, it is necessary to ensure reliable contraception. Use during pregnancy or breastfeeding. Taking Nemozol during pregnancy is contraindicated. During treatment, breastfeeding should be stopped (the safety of the drug has not been established). Children. The drug is used in children over 2 years of age. Influence on reaction speed when driving vehicles or working with other mechanisms. During the treatment period, you should refrain from driving vehicles and performing work that requires increased attention and quick reaction.

Patient reviews

The predominant number of health discussion forums and medical websites show a high percentage of positive reviews from Internet users. The advantages include simple rules of use, budget cost, and a pronounced improvement in well-being after treatment courses.

I like the option of taking the drug for prophylactic purposes, because it is important for people to be calm about their own infectious safety. Parents, concerned about the well-being of the child’s reaction to the drug, noted: effectiveness, virtual absence of side effects. The drug helps. For prevention, Nemozol is recommended to pet owners.

Features of the diet for giardiasis

Products that are not recommended for consumption:

Sweet and flour products (rolls, baked goods, chocolate, candies, honey, sugar, etc.).
Alcohol, carbonated and dairy drinks.
Spicy, fatty, smoked, pickled foods.
Pasta, sausages.
Sweet fruits.

Products that should form the basis of your daily diet:

Soups, broths.
Porridge (but only on water).
Rice broth.
Lean fish, meat.
Cheese, yogurt and cottage cheese should be unsweetened.
Boiled, raw, stewed vegetables (cucumbers, tomatoes, carrots, zucchini).
Citrus fruits, sour apples and berries (beaks, currants, etc.).
Compotes, juices, fruit juice from sour berries.

Stages of nutrition for giardiasis

The entire period of therapeutic nutrition takes place in 3 stages:

First stage. Its duration is 2 weeks. The main goal is to reduce the level of intoxication in the body and prevent the proliferation of Giardia. The diet should contain the following products: vegetable oil, various cereals with water, vegetables, baked apples, dried fruits.
The second stage will take about 3 weeks. Its goal is to remove parasites from the body. The menu should contain foods high in fiber: apples, pears, vegetables, dried apricots, blueberries.
The third stage is the final one and lasts from 2 to 3 weeks. All his efforts are aimed at creating conditions in which parasites cannot survive, as well as strengthening the body’s defenses. The menu must include fresh fruits and vegetables, various cereals with water and fermented milk products.

Diet for different ages

The menu will be slightly different for children and adults. For an adult, strict adherence to a diet is mandatory. In addition, it is advisable that at least one baked apple is eaten daily. You can cook different porridges, the only condition is that they must be cooked in water.

Example menu for giardiasis, for an adult:

In the morning: oatmeal, 1-2 pieces of cheese, apple juice.
For lunch: chicken soup, stewed zucchini and rice water.
Afternoon snack: baked apple.
For dinner: vegetable stew, rice cake, meatballs (chicken), orange juice.

Tip: the menu is presented as an example; everyone selects products from the allowed list, based on preferences. But it is desirable that they all be involved throughout all three stages of therapeutic nutrition.

Nutrition for children is a little difficult. Often a manifestation of giardiasis can be an allergy. And eating citrus fruits, honey, etc. may make the situation worse. Therefore, the menu for the child can be adjusted. If giardiasis occurs in an infant, he is transferred to artificial feeding.

Products for a child can be the same, with the exception of those to which the baby is allergic. And, unfortunately, it is not uncommon in childhood.

Example of a menu for giardiasis in older children:

For breakfast: oatmeal with meat, sour berry compote.
Lunch: broth, baked apple.
Afternoon snack: unsweetened cottage cheese.
For dinner: rice cake, vegetable puree and pear juice.

You need to follow such a diet not only until your general condition improves, but until complete recovery. This is possible provided that all treatment rules are followed. If you adhere to them, then already at the first stage of treatment you can feel an improvement in your well-being.

And, of course, everything needs to be done under the supervision of a doctor. At the end of treatment, to ensure complete recovery, you need to undergo the necessary tests.