Compound
The drug tablets contain the active component pyrantel , as well as additional components: methyl parahydroxybenzoate, gelatin, acacia gum, starch, sodium carboxymethyl starch, talc, magnesium stearate, propyl parahydroxybenzoate, colloidal silicon dioxide.
Pyrantel suspension contains the active component pyrantel , as well as additional components: sucrose, xanthan gum, sorbic acid, polysorbate 80, methyl parahydroxybenzoate, sorbitol solution 70%, propyl parahydroxybenzoate, flavorings, purified water.
Treatment results
After taking, the active components of the medicine begin to act. As a result, worms are removed from the body along with feces. The result of taking pyrantel:
- No worms were found in the feces. The cause is an insufficient dose of the drug or lack of invasion.
- Immobilized whole individuals emerge.
- Fragmentary parts of the parasites are removed.
- The helminths came out in a digested form.
The condition of removed worms is affected by:
- Individual processes of intestinal function.
- Amount and types of food eaten.
- Changes in the normal functioning of the gastrointestinal tract.
- Dosage and mode of action of the medicine.
Side effects
During treatment, the following side effects may occur:
- nervous system: drowsiness , headache , dizziness , insomnia ;
- digestive system: vomiting, diarrhea , periodic abdominal cramps , anorexia , tenesmus ;
- skin and subcutaneous tissue: urticaria , rash ;
- hepatobiliary system: increased levels of liver enzymes;
- other manifestations: feeling of weakness, increased fatigue.
Instructions for use of Pirantel (Method and dosage)
The product is used according to doctor's indications.
Pyrantel suspension, instructions for use
The suspension for children is used according to indications; it must be shaken before taking. Patients with ascariasis and enterobiasis are prescribed an average dose of 10–12 mg per 1 kg of weight in one dose. Children after 6 months should receive syrup at a dose of 2.5 ml per 10 kg of weight in one dose. Adult patients (up to 75 kg) receive 15 ml per dose. If a person’s weight exceeds 75 kg, you need to drink 20 ml of the product at one time.
To improve the effectiveness of the treatment of enterobiasis, you should very carefully adhere to all the rules of personal hygiene. It is recommended to conduct another course of therapy after three weeks.
For patients with hookworm in endemic areas or with severe infestation, the drug is prescribed based on a dosage of 20 mg per 1 kg of weight for 2 or 3 doses, treatment lasts 2-3 days.
The dosage per day is calculated as follows:
- children after 6 months receive 5 ml of syrup per 10 kg of weight;
- with a weight of up to 75 kg - 30 ml of syrup per day;
- with a weight of 75 kg - 40 ml of syrup per day.
Under conditions of mild infestation of Ankylostoma duodenale, sometimes it is enough to take a single dose of 10 mg per 1 kg.
Pirantel tablets, instructions for use
Adults are usually prescribed Pirantel in tablets. It should be taken before or during the use of food. The tablet is chewed and washed down with plenty of liquid.
How to take Pirantel for children depends on their body weight and age:
- at the age of 2-6 years, 250 mg of the drug is indicated;
- at the age of 6-12 years - 500 mg;
- children over 12 years of age and adult patients weighing up to 75 kg - 750 mg;
- adults whose weight exceeds 75 kg - 1000 mg.
If only infection with a human nematode is noted, you should take Pyrantel 5 mg per 1 kg of weight in one tablet.
For patients with enterobiasis and ascariasis, as well as with mixed infestations, the dose intended for the entire course is administered once (10 mg per 1 kg).
Patients with hookworm disease are advised to take the same dose for three days.
In case of massive infestations of Necator americanus, a dose of 20 mg/kg is indicated for two days.
You should ask your doctor for more information about how many days to take the drug, how to take tablets and suspension for adults and children for treatment, as well as for prevention for adults and children.
If the drug does not help
The drug will work with the correct dosage and treatment regimen. For each type of helminthiasis, a specific therapeutic dose is established. Failure to follow manufacturers' recommendations leads to treatment failure.
Pyrantel acts quickly - within 3-4 hours after a single dose. If the worms do not go away and the itching remains, then consultation with a specialist is necessary to adjust the dosage and treatment regimen. The drug is also being replaced with other anthelmintic drugs (based on Levamisole, Albendazole, Mebendazole).
Overdose
In case of an overdose of the drug, the patient may experience the following negative manifestations: nausea, vomiting , diarrhea , anorexia . But it should be borne in mind that pyrantel is poorly absorbed in the body, which is why signs of intoxication appear very rarely even with a significant overdose. If there is such a need, gastric lavage is prescribed; there is no specific antidote. It is important to monitor the functions of blood vessels, heart, and respiratory system.
The problem of resistance in anthelmintics
When taking medications for worms, it is important to determine whether the drug has worked. Today, the resistance of parasites to certain groups of anthelmintics is known. Resistance is the reduced sensitivity of worms to the effects of drugs. This phenomenon involves 2 real biologically distinct, but not always recognizable processes:
- Higher incidence of drug-resistant parasites.
- The existence of populations of susceptible worms that are prone to mutations (possibly caused by the effects of drugs).
Repeated use (including as part of prophylaxis) of the same drug or drugs with the same mechanism of action leads to the development of resistance in parasites that have survived previous therapy.
Today, cases of cross-resistance are more common, when resistance occurs after the simultaneous use of different drugs with different mechanisms of action. Resistance is most often expressed in reduction—the percentage loss of worms after exposure to the drug.
special instructions
The drug is prescribed with caution to people who have impaired liver function. During therapy, you should not abstain from eating or take laxative medications. This does not determine how quickly the drug works.
The drug is prescribed for simultaneous administration to all members of the family who live together. You should consider how to give the suspension or tablets to your child and follow the instructions. After completion of the study, the patient's stool is examined.
To prevent re-infection, it is important to carefully adhere to hygiene rules.
Sometimes during treatment, weakness, drowsiness , and dizziness . This should be taken into account when driving or when working with precision mechanisms.
The drug is not prescribed to people undergoing treatment for myasthenia gravis .
How long the drug takes to work depends on the diagnosis and the individual characteristics of the course of the disease.
How worms after using the drug depends on the disease.
Pyrantel is also used to treat animals. The dosage for cats and the dosage for dogs should only be determined individually by a veterinarian.
How does Pirantel work against worms?
The anthelmintic drug Pirantel blocks the vital activity of muscle tissue of parasites, paralyzing them. As a result, the helminths are completely immobilized: they lose the ability to eat, breathe and reproduce. As a result, the worms and their larvae die and are excreted naturally.
Due to the increased resistance of larval forms to Pyrantel, a second course of treatment is sometimes required, which should be carried out no earlier than a week later.
It is important to take into account the development cycle of helminths, preventing the deposition of eggs. In addition to the common pinworms and roundworms, the drug effectively destroys hookworms, which destroy the blood, often causing anemia.
Pyrantel is poorly absorbed by the mucous membrane of the stomach and intestines, so the likelihood of poisoning the body with toxins when using it is minimized. The drug does not destroy migrating helminth larvae, but kills them only in the early stages of development.
The active substance that destroys helminths accumulates maximum in the blood approximately three hours after taking the drug.
Pyrantel's analogs
Level 4 ATC code matches:
Helmintox
Analogues of this remedy are the following drugs: Nemotsid , Helmintox , Pyrantel pamoate , which contain a similar active ingredient.
Medicines have a similar effect on the body: Vermox , Biltricid , Vormin , Dekaris , etc.
Which is better: Decaris or Pirantel?
Decaris is an anthelmintic agent that has a similar effect. The drug Dekaris has more contraindications, side effects are almost the same as when using Pirantel. It is believed that Pirantel is more preferable for treating children.
Which is better: Vermox or Pyrantel?
Vermox is a broad-spectrum drug. It is especially effective against enterobiasis and trichuriasis . Which of the two drugs is preferred should be determined taking into account individual characteristics.
Which is better: Nemozol or Pirantel?
Nemozol is a drug with a wide spectrum of effects; it eliminates most known types of parasites. But only a doctor should select the medicine.
Symptoms of helminth damage
The first symptom indicating the need for examination should be any allergic reaction without obvious contact with a possible allergen. An example would be a rash that was not preceded by contact with aggressive substances or abuse of foods from a group of potential allergens. Also, long-term bronchitis, treatment of which by a therapist does not give a positive result, may indicate the presence of a parasite.
Abnormal bowel movements are another reason to get tested for helminthiasis. If the parasite has settled in the intestines, it can interfere with normal peristalsis and bowel movements. When the intestines become a haven for certain dangerous types of worms, a person may experience a lack of strength and may also develop anemia or severe lack of nutrients in the blood. This is explained by the fact that the parasite eats all the beneficial substances in the intestines faster than they can be absorbed into the blood. Therefore, weakness is also a symptom.
Pinworms infect the anus. As a result, itching in the anus is the main symptom of the presence of the parasite. The female pinworm emerges mainly at night through the anus and lays eggs in the folds of the anus, lubricating them with her secretion. The substance irritates the mucous membrane, causing itching.
Oddly enough, nighttime teeth grinding has nothing to do with helminth infection. This is an erroneous opinion based on the assumptions of older generations. A person begins to grind their teeth due to the characteristics of the nervous system.
If there are parasites in the body, the number of eosinophils in the blood increases. The number of these cells also increases with a progressive allergic reaction. Therefore, if the number of eosinophils in the biochemical blood test is higher than normal, you should be tested for helminthiasis.
Pirantel price, where to buy
The price of Pirantel suspension 15 ml is, on average, 60 rubles. The cost may be slightly lower or higher. The price of Pyrantel tablets depends on the packaging and manufacturer. On average, buy a pack of 3 tablets. possible at a price of 30 to 40 rubles.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Pyrantel tablets 250 mg 3 pcs. Ozone LLC
30 rub. order - Pyrantel Susp. for internal approx. 250mg/5ml 15mlPharmaceutical plant POLFARMA JSC Medan Department in Sieradz
60 rub. order
- Pyrantel tablets 250 mg 3 pcs.Polpharma
40 rub. order
Pharmacy Dialogue
- Pyrantel tablets 250 mg No. 3Polpharma
43 RUR order
- Pyrantel bottle 250mg/5ml 15mlMedana Pharma
61 rub. order
- Pyrantel (tab. 250 mg No. 3) Ozone LLC
29 RUR order
- Pyrantel bottle 250mg/5ml 15mlOxford Pvt.
36 RUR order
- Pyrantel (250 mg tablet No. 3)Oxford Pvt.
24 RUR order
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Pharmacy24
- Pyrantel 250 mg No. 30 tablets Kusum Healthker PVT.LTD, India
101 UAH.order - Pyrantel 15 ml suspension Medana Pharma Aktsionerne Tovaristvo, Poland
50 UAH order
- Pyrantel 250 mg/5 ml 15 ml suspension TOV "Kusum Pharm", Ukraine
25 UAH order
- Pirantel-Vishfa 250 mg/5 ml 15 ml No. 1 suspension TOV DKP Pharm.Fabrika, Ukraine
20 UAH order
PaniPharmacy
- PYRANTEL liquid Pyrantel suspension 0.25g 15ml Poland, Medana Pharma SA
41 UAH order
- Pyrantel-Vishfa liquid Pyrantel-Vishfa suspension. oral 250mg/5ml fl 15ml Ukraine, Zhitomir FF LLC
27 UAH order
- PYRANTEL liquid Pyrantel suspension 250mg/5ml 15ml Ukraine, Kusum Pharm LLC
29 UAH order
- PYRANTEL tablets Pyrantel tablets. 250 mg No. 30 India, Kusum Healthcare
107 UAH order
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