To treat digestive problems, preparations based on natural herbs and their extracts are often used. Iberogast is an effective remedy that helps with irritable bowel syndrome and all types of digestive disorders. It relieves acute symptoms of severe gastrointestinal diseases and improves well-being.
Composition, release form
"Iberogast" are drops that need to be taken orally, dissolved in clean drinking water. They are available in 100 ml bottles. Inside the bottle is a dark brown liquid that may be clear or slightly cloudy. If the drug is stored for a long time without use, a small sediment may appear at the bottom.
The composition includes liquid extracts of various medicinal plants and their individual parts:
- Iberian bitter (15 ml) - fresh whole plant is kept in ethanol with a concentration of 50% in a ratio of 1: 1.5–2.5.
- Angelica officinalis (10 ml) - dry roots. The extractant was 30% ethanol in proportions 1:2.5–3.5.
- Chamomile (20 ml) - dried flowers in extractant (ethyl alcohol 30%) in a ratio of 1:2.0–4.
- Caraway seeds (10 ml) - dry fruits are kept in ethyl alcohol 30% in proportions 1: 2.5–3.5.
- Milk thistle (10 ml) - dry fruits, the extractant for which is ethanol 30%. The proportions are 1:2.5–3.5.
- Melissa officinalis (10 ml) - dry leaves are kept in ethyl alcohol 30% in a ratio of 1:2.5–3.5.
- Peppermint (5 ml) - dry leaves in ethanol 30% and proportions 1: 2.5–3.5.
- May celandine (10 ml) is a dry herb soaked in ethyl alcohol in proportions 1: 2.5–3.5.
- Licorice naked (10 ml) - dry roots, soaked in 30% ethanol in a ratio of 1: 2.5–3.5.
Ethyl alcohol 31% was used as an additional component. In pharmacies you can find bottles with a volume of not only 100 ml, but also 20 ml and 50 ml. The herbal medicine is stored in cardboard packages.
Iberogast
Iberogast
® (English
Iberogast
®) is a herbal medicine that has anti-inflammatory and myotropic antispasmodic effects on the smooth muscles of the gastrointestinal tract.
Active ingredients of Iberogast
The active ingredients of Iberogast are alcoholic extracts of 9 medicinal plants:
- Iberis bitter
(synonym
Iberian bitter
; lat.
Iberis amara
) is a herbaceous plant of the cruciferous family. It grows mainly in fields. The active ingredients are flavonoids and glycosides of mustard oil (glucosinolates), contained in all parts of the plant. The extract from the fresh Iberian bitter plant in Iberogast acts as a prokinetic agent, increasing the tone of the smooth muscles of the gastrointestinal tract. - Volume fraction in drops of Iberogast extract of liquid whole fresh Iberis bitters plant (extractant ethanol 50%) 1:1.5-2.5 - 15.0% (15.0 ml per 100 ml drops)
Chamomile in Linnaeus Garden, Uppsala, Sweden |
(synonym
chamomile
; lat.
Matricaria chamomilla
) is an annual herbaceous plant with a strong specific odor. Belongs to the Asteraceae family. It grows in meadows, along roadsides, on slopes and blooms from May to June. The active ingredients are essential oils, aromatic carboxylic acids, coumarins and flavonoids. The extract has anti-inflammatory, antibacterial, antispasmodic and wound-healing effects.
- The volume fraction in drops of Iberogast liquid extract of dry flowers (lat. Matricariae flos
) of chamomile (extractant ethanol 30%) is 1: 2.0-4.0 - 20.0%.
(lat.
Mentha piperita
) is a herbaceous plant of the mint genus of the Lamiaceae family that is the result of crossing two different wild species of mint and reproduces only by shoots. Active ingredients: essential oils, tannins. Peppermint extract eliminates bloating, has an antispasmodic effect, stimulates bile production, and has an anti-inflammatory effect.
- The volume fraction in drops of Iberogast liquid extract of dried peppermint leaves (extractant ethanol 30%) is 1: 2.5-3.5 - 5.0%.
(synonym
May celandine
, lat.
Chelidonium majus
) is a herbaceous plant of the poppy family. It grows in bushes or near human habitation. The active ingredients are alkaloids and organic acids. The extract has an antispasmodic effect on the biliary tract and gastrointestinal tract, and stimulates gastric motility.
- The volume fraction in drops of Iberogast liquid extract of dry herb dry celandine (extractant ethanol 30%) is 1:2.5-3.5 - 10.0%.
(synonym
Angelica officinalis
, lat.
Archangelica officinalis
) is a plant up to 2 meters high from the Umbrella family. It grows mainly on river banks and water meadows. The active ingredients are essential oils, coumarins, tannins and flavonoids. It has a stimulating effect on digestion and an antispasmodic effect, primarily on the stomach and intestines.
- The volume fraction in drops of Iberogast of the liquid extract of dry roots of Angelica officinalis (extractant ethanol 30%) is 1: 2.5-3.5 - 10.0%.
(lat.
Carum carvi
) is a biennial plant 30–100 cm high from the Umbelliferae family. Cumin is one of the most commonly found wild plants in Germany. The active ingredients are essential oils, coumarins, flavonol glycosides and flavonoids. Dry cumin fruit extract has a bactericidal and antispasmodic effect. Improves tolerance to foods that cause bloating. such as cabbage or legumes.
- The volume fraction in drops of Iberogast extract of liquid dry fruits of caraway seeds (extractant ethanol 30%) is 1: 2.5-3.5 - 10.0%.
(synonym:
lemon balm
, lat.
Melissa officinalis
) is a herbaceous plant of the Lamiaceae family, 30–70 cm high, exuding a strong lemon aroma. Originally comes from Asia Minor and the eastern Mediterranean, cultivated in gardens. Active ingredients: essential oils, tannins, triterpene acids, bitterness and flavonoids. Dry leaf extract has a calming effect, eliminates bloating, and has antispasmodic properties.
- The volume fraction in drops of Iberogast liquid extract of dry leaves of lemon balm (extractant ethanol 30%) is 1: 2.5-3.5 - 10.0%.
(lat.
Silybum marianum
) is a plant from the Asteraceae family, 60–150 cm high with large purple-red flowers surrounded by a prickly basket. Originates from Mediterranean and Eastern countries, it is often grown in gardens as an ornamental plant. The active ingredients are flavonolignans (silymarin, silybin), neolignan and flavonoids. Dry fruit extract has a cytoprotective effect on the stomach and liver and stimulates the regeneration of liver cells.
- The volume fraction in drops of Iberogast liquid extract of dry fruits of milk thistle (extractant ethanol 30%) is 1: 2.5-3.5 - 10.0%.
(synonym
licorice
, lat.
Glycyrrhiza glabra
) is a perennial (up to 15 years) plant of the legume family, 1–2 m high. It grows mainly in arid areas, on clay and sandy soils and originally comes from the Mediterranean. The active ingredients are glycyrrhizic acid, flavonoids, phytosteroids and coumarins. The extract has an antispasmodic effect and accelerates the healing of stomach ulcers.
- The volume fraction in drops of Iberogast of the liquid extract of dry roots of Angelica officinalis (extractant ethanol 30%) is 1: 2.5-3.5 - 10.0%.
Indications for use of Iberogast
Iberogast is used to treat:
- functional disorders of the digestive tract, manifested by heaviness in the epigastric region, stomach or intestinal cramps, belching, nausea, flatulence, constipation, diarrhea, or their alternation
- irritable bowel syndrome (IBS)
and also as part of complex therapy:
- gastritis
- stomach and duodenal ulcers
Contraindications to the use of Iberogast
Iberogast is contraindicated in:
- hypersensitivity to the components of the drug
- calculous cholecystitis
- patient age under 18 years
Since Iberogast contains ethyl alcohol, it should be used with caution when:
- liver diseases
- alcoholism
- traumatic brain injury
- brain diseases
Method of administration of Iberogast and dose
Iberogast is taken orally, with a small amount of water, 3 times a day, 20 drops, before or during meals for 4 weeks. The doctor may increase the duration of therapy or prescribe repeated courses of treatment.
Use of Iberogast by pregnant women, children and breastfeeding
Iberogast is not recommended for use by pregnant women, nursing mothers and children under 18 years of age.
general information
Iberogast is recommended by the Rome IV criteria (2016) for the treatment of functional dyspepsia.
Interest in it in Germany arose within the framework of the concept of multi-target or multi-target therapy, which involves, instead of prescribing several drugs that affect individual links in the pathogenesis of a given disease, the use of one drug that simultaneously affects several links. Iberogast normalizes accommodation of the fundus of the stomach, improves the evacuation of gastric contents, reduces visceral hypersensitivity, reduces the secretion of hydrochloric acid, and has a gastroprotective effect, improving gastric mucus formation. Conducted clinical studies and meta-analyses based on their results indicated the high effectiveness of the drug in patients with FD (especially with postprandial distress syndrome) and its good tolerability. The feasibility of using Iberogast is also determined by the frequent combination of FD with IBS, in which its administration also normalizes intestinal motility and reduces the severity of pain (Sheptulin A.A., Kurbatova A.A.). This recommendation was confirmed in 2022 by the Clinical Guidelines of the Russian Gastroenterological Association for the diagnosis and treatment of functional dyspepsia.
Manufacturer (license holder) Bayer HealthCare AG (Bayer Consumer Care AG), Germany.
See: Instructions for use of the drug for medical use Iberogast. Bayer Consumer Care AG, Switzerland. 07/31/2014
Publications for healthcare professionals regarding the use of Iberogast
- Ganzii E.B., Solodovnichenko I.S., Voloshina L.G. The use of the drug iberogast in complex therapy in children with gastroduodenal pathology. Materials of the XX Anniversary Congress of Pediatric Gastroenterologists of Russia. - 2013. P. 88-89.
- Sheptulin A.A., Kurbatova A.A. New Rome criteria for functional dyspepsia IV revision // RZHGGK. – 2016. – No. 26(4). pp. 124-128.
- Ivashkin V.T., Maev I.V., Sheptulin A.A. and others. Clinical recommendations of the Russian Gastroenterological Association for the diagnosis and treatment of functional dyspepsia // RZHGGK. 2022. No. 27 (1). pp. 50–61.
On the website GastroScan.ru in the “Literature” section there is a subsection “Anspasmolytics”, containing articles addressing the use of antispasmodics.
Video for medical university students
Still from “Iberogast” from a video lecture for 3rd year students of the Faculty of Medicine of PSPbSMU named after. acad. I.P. Pavlova: Melnikov K.N. Drugs affecting the gastrointestinal tract
On the website in the “Video” section there is a subsection for patients “Popular Gastroenterology” and subsections “For Doctors” and “For Medical Students and Residents”, containing video recordings of reports, lectures, webinars in various areas of gastroenterology for healthcare professionals and medical students.
Iberogast has contraindications, side effects and application features; consultation with a specialist is necessary. Back to section
How it affects the body
Iberogast normalizes the tone of smooth muscles of all organs of the digestive system and has an anti-inflammatory effect. It does not affect peristalsis, but effectively relieves spasms. If the gastrointestinal tract has low tone, then the medicine stimulates and tones it.
This drug is able to fight 6 subspecies of the dangerous bacterium Helicobacter pylori: it suppresses their growth. Iberogast has a beneficial effect on the stomach:
- reduces the intensity and frequency of mucosal ulceration;
- increases the amount of E2 (mucoprotective prostaglandin) in the mucous membrane;
- normalizes the secretion of hydrochloric acid;
- improves reproduction and mucin levels;
- reduces the number of leukotrienes.
These effects are very useful for patients suffering from gastritis and stomach ulcers. This reduces the risk of complications and the development of more severe diseases.
The effect of Iberogast on gastritis
The main culprit of gastritis and gastric ulcers is the bacterium H. pylori, which destroys the walls of the main organ of the gastrointestinal tract - the stomach. Due to the fact that the product contains extracts of chamomile, peppermint, cumin fruits, Iberogast has an antimicrobial effect.
Once in the body, the drug reduces the growth of bacteria, stopping the progression of the disease. Here we can highlight the main advantage of the drug - the possibility of use when other drugs are contraindicated.
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Indications
Iberogast is prescribed for many diseases and painful conditions:
- stomach ulcer;
- gastritis;
- duodenal ulcer;
- irritable bowel syndrome;
- stomach cramps;
- various digestive disorders (constipation, vomiting, flatulence, belching);
- feeling of heaviness in the epigastric area;
- any functional disorders of the gastrointestinal tract.
In most cases, Iberogast is prescribed along with other medications in the treatment of diseases and is not the only prescribed remedy. For radical treatment, the doctor chooses other drugs, and this drug serves as support and consolidation of the achieved result.
Indications for use of Iberogast
There is a whole list of indications for taking a medicine like Iberogast, which is what makes it so popular. Since the main effect is on the gastrointestinal tract, the main indications can be noted:
- Therapy of functional disorders in the stomach, intestines, including irritation in the intestines.
- Complex types of therapy for diseases such as gastritis, peptic ulcers of the stomach and intestines.
- Non-periodic use of the medicine can improve appetite and relieve symptoms of overeating (belching, nausea).
- Combating stool disorders - constipation or diarrhea.
It is possible to achieve a therapeutic effect for such a large number of diseases thanks to the selective action of Iberogast in different parts of the stomach and intestines. For example, combating decreased motor activity of the stomach can relieve a person from painful constipation.
Contraindications
Iberogast has many contraindications. With these diagnoses you cannot take drops:
- allergy to medication components;
- calculous cholecystitis (gallbladder stones in combination with its inflammation);
- period of pregnancy and lactation;
- age under 12 years.
For other conditions and diseases, drops should be taken with great caution:
- brain injuries and diseases;
- liver diseases;
- alcoholism.
The patient must strictly follow the doctor's recommendations and prescriptions. If the condition worsens, you should consult a doctor.
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** The Drug Directory is intended for informational purposes only. For more complete information, please refer to the manufacturer's instructions. Do not self-medicate; Before starting to use Iberogast, you should consult a doctor. EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the site does not replace medical advice and cannot serve as a guarantee of the positive effect of the drug.
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** Attention! The information presented in this medication guide is intended for medical professionals and should not be used as a basis for self-medication. The description of the drug Iberogast is provided for informational purposes and is not intended for prescribing treatment without the participation of a doctor. Patients need to consult a specialist!
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Overdose and side effects
Cases of overdose of the herbal medicine "Iberogast" are still unknown, but exceeding the dose is not recommended, otherwise complications and other unpleasant symptoms may occur.
Iberogast may cause some side effects:
- digestive disorders (diarrhea, nausea, vomiting);
- dyspnea;
- skin allergies.
If side symptoms occur, you need to visit a doctor and stop taking the drug.
Important to remember
If your condition has not improved within 14 days of taking the medicine, you should consult a doctor.
The product contains ethanol, which can affect the reaction speed and ability to concentrate. This substance increases blood alcohol levels. During the course of treatment, you must be very careful when handling complex machinery (construction, repair, industrial) and driving a car. It is better to temporarily stop driving altogether.
This product has no complete analogues. Partial analogues include “Zakofalk”, “Salofalk”, “Kolofort”, “Pentasa”, “Befungin”, “Gastrarex”, “Mesakol”, “Gastroguttal”, “Itomed”, etc.
Action for hemorrhoids and heartburn
Heartburn can appear both in pathological conditions in the stomach and in a healthy person. It largely depends on what kind of food a person takes. Heartburn can be affected by alcohol intake, stress, and excess weight.
For heartburn, taking Iberogast is also indicated, since after a dose of the medicine, the smooth muscles in the stomach relax and toning occurs. This leads to the fact that intra-abdominal pressure decreases and undigested stomach contents stop entering the esophagus.
But for hemorrhoids, Iberogast is indicated only during a course of treatment with other drugs. Thanks to taking Iberogast, the patient can regulate his bowel movements, that is, eliminate dangerous constipation, which in turn aggravates the course of hemorrhoids. A doctor will help you choose a course of treatment.