Emanera is an antiulcer drug and proton pump inhibitor prescribed to patients for the treatment of GERD, gastric and duodenal ulcers. There are significant contraindications and age restrictions.
Before starting the course, drug interactions must be taken into account. The product is not overpriced: 80–360 rubles. per package, depending on the dosage and number of capsules. Only a gastroenterologist is involved in the selection of Emanera analogues that are cheaper.
pharmachologic effect
Manufacturer: KRKA, Slovenia
Release form: capsules
Active ingredient: esomeprazole
The active ingredient of Emanera is esomeprazole magnesium dihydrate. The drug belongs to the group of proton pump inhibitors, which help reduce the secretion of gastric juice and also has an antiulcer effect.
The active substance suppresses the secretion of hydrochloric acid in the digestive organ due to its targeted action. Has a cumulative effect. The effect of the drug is observed an hour after administration. After a five-day course, the concentration of hydrochloric acid decreases by 85–89%.
In most patients, after a month of taking 40 mg of Emanera, reflux esophagitis heals. There is an increased effectiveness of the drug in the prevention of gastric and duodenal ulcers in patients taking NSAIDs and selective COX-2 inhibitors.
Main differences between drugs
Emanera is the S-isomer of Opeprazole, that is, its “mirror image”. Both substances have similar pharmacological activity, but differ in the ways in which the mechanism of action is implemented. Esomeprazole is a weak base; it is able to accumulate and transform into active forms in the secretory tubules of the gastrointestinal mucosa. There, the drug inhibits the activity of the proton pump and reduces acid secretion.
The effect of taking Emanera is achievable only an hour after administration, and Omeprazole begins to fully demonstrate its effectiveness after 30 minutes. But when considering the prolonged therapeutic effect, esomeprazole is significantly superior to omeprazole and is a powerful remedy for protecting the stomach, esophagus, and duodenum from the irritating effects of acid.
Emanera can be used to prevent stomach diseases - it provides a very long-term protective effect.
According to doctors, the comparison of Omeprazole and Emanera - which is better, what to choose for the patient, is not correct. Despite the availability of more modern drugs, Omeprazole is the most effective for the treatment of stomach ulcers, therefore it is constantly recommended for use by gastroenterologists.
Emanera - instructions for use
According to the instructions for use, Emanera is taken orally. It is recommended not to chew the capsules, but to take them with a sufficient amount of liquid.
Dosage of the drug according to the age category of the patient
| Age | Diagnosis | Course duration and dosage |
| Older patients | GERD | Treatment: 40 mg once a day for a month. In the absence of a positive result, therapy is extended. Duration of treatment for prophylactic purposes: 20 mg once a day. Symptomatic treatment: 20 mg once a day. Adjustment of the duration of use and dosage is carried out by a gastroenterologist after additional examination. |
| Stomach and duodenal ulcers | As part of combined antibacterial therapy: 20 mg 2 times a day for a week. When taking NSAIDs: -treatment of ulcers: 20 mg per day, course duration – no more than 1.5 months; -ulcer prevention: 20 mg per day. | |
| Prevention of recurrent bleeding from peptic ulcers after intravenous therapy | 40 mg per day for a month. | |
| In conditions characterized by increased gastric secretion | 40 mg 2 times a day. Then the dose is adjusted, the duration of treatment depends on the clinical indications. | |
| Patients over 12 years old | Ulcer caused by Helicobacter pylori | The duration of therapy is from 7 to 14 days. The dosage depends on the patient’s body weight: - 30-40 kg and more: combination treatment with other antibiotics. Emanera 20 mg 2 times a day for 7 days. |
The drug is not recommended for patients of a younger age category, as well as for those with renal failure. In case of severe liver disorders, the daily dose of Emaner should not exceed 20 mg. It is necessary to exclude the course of treatment with the drug during pregnancy and during breastfeeding.
How to take Emanera - before or after meals
Directions for use: inside. It is recommended to drink Emanera capsules before or during meals.
Emanera and Omeprazole - indications
Emanera capsules (sometimes mistakenly called tablets) are most often prescribed to be taken for gastroesophageal reflux disease, or GERD. This disease can lead to the development of reflux esophagitis over time, and the medicine helps prevent it from becoming chronic.
They take the drug for a long time (up to a year) to prevent relapses of GERD.
In complex therapy with antibiotics, Emanera is prescribed to treat infections caused by Helicobacter pylori bacteria. Emanera also treats the following diseases:
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- peptic ulcer, peptic ulcer;
- damage to the duodenum - ulcers, erosions;
- Zollinger-Ellison syndrome;
- primary hypersecretion of acid;
- pancreatitis in chronic form (in complex therapy).
It is often recommended to take the medicine simultaneously with nonsteroidal anti-inflammatory drugs and other medications that lead to inflammation of the gastrointestinal mucosa and can cause gastritis and ulcers.
Omeprazole's first indications include the treatment and prevention of peptic ulcers, erosive gastritis, and duodenitis. With less effectiveness, but the drug can be used to treat and prevent exacerbation of GERD, superficial gastritis, and any type of hypersecretion of hydrochloric acid.
Analogues of Emanera
Pharmacies offer a wide range of foreign and domestic analogues and substitutes for Emanera, differing in dosage, composition, release form, indications, course duration and cost.
When choosing a substitute, you should pay attention to special instructions and the possibility of combining the drug with other medications.
Prices for Emanera analogues
| Drug name | price, rub. | Manufacturer country |
| Control | 309-597 | Germany |
| Pariet | 1572-4544 | Switzerland |
| Nexium | 210-1800 | |
| Rabeprazole | 240-460 | Russia |
| De-Nol | 370-1000 | |
| Omeprazole | 46-100 | |
| Ultop | 190-550 | |
| Dexilant | 1300-2500 | Japan |
| Khairabesol | 390-420 | India |
| Omez | 75-450 | |
| Razo | 240-470 | |
| Nolpaza | 190-810 | Russia, Slovenia |
The cost of analogues depends on the packaging, country of manufacture and point of sale.
Control
Manufacturer: Takeda Pharmaceuticals, Germany
Release form: tablets
Active ingredient: pantoprazole
A substitute for Emanera Controloc is an antiulcer drug prescribed to eliminate the symptoms of mild GERD. There are age restrictions and contraindications, which it is recommended that you familiarize yourself with before starting the course. To eliminate side effects from analogue therapy, you must follow the prescribed dosage.
Controloc is taken orally before meals. The tablets should not be chewed; they should be taken with a sufficient amount of liquid. Daily dose – 20 mg. The duration of the course of treatment is no more than 14 days. The analogue is prohibited from being taken for preventive purposes; it is dispensed with a doctor's prescription.
Pariet
Manufacturer: Johnson & Johnson, Switzerland
Release form: tablets
Active ingredient: rabeprazole
Pariet is recommended for stomach and duodenal ulcers and other disorders. This analogue of Emanera can also be used in a complex of antibacterial therapy against Helicobacter pylori. The product has contraindications, age restrictions - up to 12 years. You can take tablets regardless of the time of day or meals. Pariet is available without a prescription.
Rabeprazole
Manufacturer: TATHIMPHARMPREPARATIONS, Russia
Release form: tablets
Active ingredient: rabeprazole
Rabeprazole is an analogue of Emanera 40 mg, which is prescribed to patients with gastric and duodenal ulcers in the acute phase, and which was provoked by Helicobacter pylori, with GERD.
The product also has contraindications and age restrictions. The drug is taken orally, the daily dose is 10–20 mg.
The duration of the course depends on the indications. The analogue is available by prescription
De-Nol
Manufacturer: ASTELLAS PHARMA, Russia
Release form: tablets
Active ingredient: bismuth tripotassium dicitrate
The De-Nol analogue also belongs to antiulcer and anti-inflammatory drugs with bactericidal activity against Helictobacter pylori. The active substance is practically not absorbed from the gastrointestinal tract, but a small amount can enter the blood. It is excreted in feces and urine.
De-Nol is recommended not only for ulcers, but also for gastritis, irritable bowel syndrome, and functional dyspepsia. The analogue has contraindications, but is approved for treatment in patients over 4 years of age.
Analogues, contraindications, side effects
Among analogues in pharmacies you can find a number of drugs that have a similar effect.
| A drug | Compound | Price, rubles |
| Nolpaza | Pantoprazole | 220 |
| Omez | Omeprazole | 75 |
| Ranitidine | Ranitidine | 35 |
| Ultop | Omeprazole | 130 |
| Famotidine | Famotidine | 15 |
| Nexium | Esomeprazole | 1500 |
Contraindications for the drugs include age under 18 years for Omeprazole, under 12 years for Emanera, and lactation. Omeprazole should not be taken during pregnancy; Emanera should not be taken in the early stages of gestation; from the second trimester it can be taken for health reasons. Both drugs are prescribed with caution in renal failure.
Serious side effects are very rare. Most often, reversible reactions occur - nausea, abdominal pain, flatulence, taste disturbances. Very rarely, hepatitis, hallucinations, headaches, and blood disorders were recorded (mainly in patients with diseases of the relevant organs). In general, both drugs are well tolerated and can be used for long-term therapy.
Emanera or Omeprazole – which is better?
, Russia
Release form: capsules
Active ingredient: omeprazole
Omeprazole, like many analogues of Emanera 20 mg, is available in capsule form and has the same mechanism of action, indications, method of administration and dosage. The substitute does not accumulate in the body, side effects may occur during treatment, and there are contraindications.
Differences between drugs:
- Emanera is a modern medicine;
- Omeprazole has less bioavailability and effectiveness;
- Release of dosages;
- Emanera has a long half-life, so it lasts longer.
The difference between these drugs is their affordability. It’s difficult to say unequivocally that it’s better. Both remedies have both positive and negative effects. Reviews from doctors are not very different.
Prices
Let's compare the cost of the most popular form of Emanera and its substitutes - capsules and tablets containing 20 mg of the active substance.
| Name of the medicine | Number of tablets/capsules per package | Price, rub |
| Omeprazole of domestic production | 30 | From 38 |
| Imported omeprazole | 30 | From 98 |
| Omez | 30 | From 200 |
| Nexium | 14 | 140 |
| Nolpaza | 28 | 278 |
| Emanera | 28 | 280 |
Emanera or Nexium – which is better?
, Sweden
Release form: tablets
Active ingredient: esomeprazole
The effectiveness of the analogue Nexium and Emanera is similar, but still the second drug has a more pronounced therapeutic effect. The duration of treatment is the same period. Dispensed by prescription.
As for the risks during use, they are also the same. There are contraindications and age restrictions.
The difference between the drugs is in cost. Emanera is a cheaper drug, but no less effective. Doctors' reviews about them are the same.
Synonyms
The following trade names are offered in Russia:
- Nexium;
- Esomeprazole of domestic and imported production.
Nexium
The drug containing esomeprazole is produced in Britain and is an original branded drug.
Nexium is the best alternative to Emanera
The medicine has gone through a full pharmaceutical cycle, including development and study in the laboratory, as well as clinical studies on patients with hyperacid conditions. Numerous observations have proven its safety and effectiveness. This is the best medicine among ezoomeprazole products.
The difference from other analogues is a wide range of release forms. It is produced not only in tablets, but also in soluble pellets (microgranules) and injections.
Emanera or Omez – which is better?
, India
Release form: capsules
Active ingredient: omeprazole
The Omez analogue, like Emanera, is available by prescription, is inexpensive, and is recommended for ulcerative lesions of the gastrointestinal tract.
The difference between these two drugs is their effectiveness. Omez, compared to Emanera, is not as effective, but it has fewer contraindications and does not contribute to the body’s addiction.
According to experts, one of the proposed remedies can be used to treat ulcers.
Domestic analogues
In the Russian Federation, only the generic Esomeprazole and its cheap predecessor, Omeprazole, are produced.
Esomeprazole
The advantage of tablets is their budget price. However, unlike the original, it has not undergone any testing and does not have a wide variety of dosage forms.
Difficulties may arise when purchasing due to the low popularity of the drug.
Omeprazole
The cheapest analogue.
Omeprazole is not a complete copy of Emanera
It is produced not only at domestic, but also at imported factories. Sold in all pharmacies. Like other unequal substitutes, it can only be used on the recommendation of a specialist.
Emanera or Nolpaza - which is better?
, Russia
Release form: tablets
Active ingredient: pantoprazole sodium sesquihydrate
The Emanera analogue Nolpaza is recommended for ulcerative lesions of the gastrointestinal tract. The drugs affect the production of gastric juice, have the same duration of therapeutic effect, and belong to the group of proton pump inhibitors.
Nolpaza is more effective against Helicobacter pylori. They are similar in cost and contraindications, but in terms of effectiveness and safety they are better than Emanera. Reviews from doctors about these medications are positive.
Emanera or Razo - which is better?
, India
Release form: tablets
Active ingredient: rabeprazole
Razo is considered an effective analogue, which is safe, has a small number of contraindications and side effects. The remedy also helps in the treatment of gastrointestinal ulcers.
Before starting the course, be sure to take into account the fact that Emanera is more addictive to the body. In any case, a preliminary consultation with a gastroenterologist is required.
The drugs are similar in price and effectiveness, so they can replace each other.
Emanera analogues are medicines with similar indications, but differing in duration of use, composition, contraindications and effectiveness. To make the right choice, you need to consult a doctor and make a correct diagnosis.
What analogues exist
Conventionally, substitutes can be divided into two categories:
- drugs with similar pharmacological actions, but different in chemical composition (based on omeprazole, pantoprazole, rabeprazole);
- medications with a similar composition are generics containing esomeprazole.
It is optimal to use analogues of the active substance, since they are maximally similar in their pharmacological characteristics to the original medicine.
