Instructions
Nurofen and Analgin are antipyretic and anti-inflammatory drugs used for the treatment of acute otitis media, viral diseases, and rhinosinusitis. The drugs provide pain relief in a short time and are well tolerated by patients.
Nurofen and Analgin are antipyretic and anti-inflammatory drugs used for the treatment of acute otitis media, viral diseases, and rhinosinusitis.
How they affect the body
NSAIDs (Nurofen) have an antipyretic effect and block COX-1 and COX-2. Interferes with the synthesis of prostaglandins. 90% bound to plasma proteins and excreted by the kidneys.
The pyrazolone derivative (Analgin) has an analgesic and antispasmodic effect.
The medication affects the formation of prostaglandins and has a high absorption rate of 90%. Penetrates into the fetus through the placental barrier. A small amount of metabolites are found in breast milk.
How many times can Nurofen be given to a baby?
The effect of the drug begins an hour after the first dose. The decrease in temperature can continue for up to half an hour until the values drop to normal levels. The antipyretic effect can last up to 8 hours. However, with severe inflammatory processes, the fever may return after 4-5 hours. An infant can be re-given a single dose of the drug both in the form of suppositories and in the form of syrup after 4 hours if the temperature begins to rise again. A baby can receive up to 5 permissible single doses per day.
Indications for use
Nurofen (Ibuprofen) is prescribed for diseases such as:
- toothache;
- migraine attack;
- radiculitis;
- flu;
- cold.
Nurofen is prescribed for diseases such as toothache, migraine, radiculitis, flu, and colds.
Metamizole sodium is used for conditions such as:
- myalgia;
- joint pain;
- hepatic or renal colic;
- injuries;
- burns;
- tumor.
Which is safer Nurofen or paracetamol
Ibuprofen, which is part of the drug, is contraindicated for people with chronic bronchial diseases, in particular asthma. In addition, Nurofen should not be taken by patients with intolerance to the active substance, pregnant women, patients with heart failure, diagnosed liver failure and gastrointestinal bleeding.
Contraindications to taking paracetamol are the neonatal period, individual intolerance to the drug, and gastric ulcers, including erosion and inflammation of the gastrointestinal mucosa.
Analgin or Nurofen - which is better to take?
Ibuprofen has fewer side effects than an antipyretic. The analgesic effect of NSAIDs is 30 minutes, the antipyretic effect lasts 4 hours. To eliminate elevated body temperature, it is better to use Ibuprofen.
Metamizole sodium causes side effects, but quickly eliminates pain, for example, during an oncological process.
Analgin causes side effects, but quickly eliminates pain, for example, during an oncological process.
What is Nurofen syrup and tablets for?
The action of Nerofen is explained by the presence of ibuprofen in the composition, which, by acting on the thermostat in the brain, relieves fever and returns the temperature to normal values.
In addition, ibuprofen inhibits the synthesis of prostaglandins, which are mediators of pain. Which explains its analgesic effect. This is why Nurofen is indicated for:
- high body temperature;
- toothache;
- headache;
- muscle pain;
- for adverse reactions after DTP.
special instructions
During treatment with NSAIDs, the blood picture, kidney and liver condition are monitored. Metamizole sodium provokes the development of agronulocytosis.
Pregnancy and lactation
To treat colds, Ibuprofen is prescribed to the expectant mother under the supervision of a doctor. The drug is contraindicated in the last months of pregnancy. During treatment with the medication, stop breastfeeding.
Childhood
If the flu occurs with a fever above 38°C or the patient has central nervous system diseases, he is prescribed metamizole sodium intramuscularly in combination with Suprastin and No-shpa in dosages appropriate to the child’s age. Ibuprofen is safe for chickenpox as an antipyretic drug in children from 6 months of age.
Elderly age
The use of metamizole sodium in adults often leads to damage to the stomach, liver, and allergies. In an elderly person with heart disease, the condition worsens after regularly taking an analgesic.
If Nurofen does not bring down the temperature: what to do
When the thermometer rises above 39˚C, absorption of substances from the stomach may stop. This means that taking medications orally may not have an effect. This happens especially often when the patient washes down the tablet or syrup with cold water. Once in the stomach, cold liquid forces the vessels of the gastric walls to contract, as a result of which they cannot fully pass substances through their walls.
In this case, doctors recommend giving preference to rectal suppositories at high temperatures exceeding 39˚C. The suppository, once in the rectum, quickly dissolves, and ibuprofen immediately enters the bloodstream through the intestinal walls. After 30-40 minutes, the patient’s temperature begins to decrease.
Reviews
Semyon Viktorovich, 48 years old, Tobolsk: “I don’t believe the information about the dangers of Analgin. When the pain is severe, the drug is always at hand. The medicine is cheap and helps to cope with any ailment, especially high fever.”
Olga Nikolaevna, 28 years old, Tver: “I always keep Nurofen in my medicine cabinet. It lowers a child's temperature better than Paracetamol tablets. The medicine eliminates muscle pain and body aches. Sometimes I take the drug with Omez to protect my stomach. The medicine works well, the price is reasonable.”
After how many hours can Nurofen be given?
Due to the fact that the drug is quickly and almost completely absorbed from the gastrointestinal tract, its maximum concentration in human plasma is reached after 30 minutes. This suggests that after taking the drug on an empty stomach, the patient’s temperature should begin to decrease within 40 minutes. When taking a single dose of the drug after a meal, the antipyretic effect should appear after an hour.
If the temperature has not started to decrease after an hour, you can give another antipyretic drug. In this case, it is better to give preference to paracetamol. Nurofen can be taken again no earlier than 4 hours after the first use.
The same dosage regimen also applies in the opposite direction, when the question arises of how long after paracetamol can be taken Nurofen. If taking paracetamol after an hour does not work, you can switch to ibuprofen.
What is the difference between Nurofen and Analgin
Nurofen is safe, the main thing is to maintain the dosage. It relieves fever, pain and can be prescribed to infants. The medication helps suppress the production of prostaglandins, which contribute to the occurrence of inflammation.
Analgin is very effective in the fight against pain; it is cheap, but nevertheless has a negative effect on the kidneys, liver, heart and leukocytes. It only helps for a short time in getting rid of the disease, but, overall, it is harmful to the body.
What CAN and NOT do when a child has a high temperature (7 rules)
✔1. How and when to bring down a child's temperature
We knock it down if it is above 39. Your task is to reduce the temperature to 38.9 C in the butt (38.5 C in the armpit). • to reduce fever, use paracetamol (acetominophen), ibuprofen. Never use aspirin, especially if your child has chickenpox. • undress the child (do not wrap him up!). Don't forget about cool, fresh air in the room. • To reduce the temperature, you can also use cool baths (water temperature corresponds to normal body temperature). • do not use alcohol wipes, especially on young children. Remember, alcohol is poison for a child.
✔2. Why do Paracetamol and Ibuprofen not always help?
The fact is that all drugs in pediatric practice are calculated based on the weight of a particular child. Medicines must be taken, correctly calculating the dose for the weight of a particular child, using special measuring syringes. Manufacturers, especially of cheap paracetamols, for some reason underestimate doses, and focusing on the recommendation - “from 6 months to 3 years” is also not reasonable, since one cannot The dose of the drug is suitable for a child weighing from 8 to 18 kg.
✔3. How to take antipyretics correctly? (Calculate the dose of the medicine)
Paracetamol (Panadol, Efferalgan, Cefekon D) single dose of the drug – 15 mg/kg. That is, for a child weighing 10 kg, a single dose will be 10 kg X 15 = 150 mg. For a child weighing 15 kg - 15X15=225 mg. This dose can be given up to 4 times a day, if necessary.
Ibuprofen (nurofen, ibufen) Single dose of the drug 10 mg/kg. That is, a child weighing 8 kg needs 80 mg, and a child weighing 20 kg needs 200 mg. The drug can be given no more than 3 times a day.
The drugs reduce the temperature within an hour and a half, by about 1-1.5 degrees; you should not expect a decrease in temperature to the “normal” 36.6.
✔4. What drugs should NOT be given to a child?
Analgin (metamizole sodium). The use of the drug in the civilized world is not approved due to its high toxicity and inhibitory effect on hematopoiesis. In Russia it is widely used, especially in emergency situations, as part of a “lytic mixture”. A single administration of the drug is possible in conditions where other, safer drugs are not available. But constant use of analgin with every increase in temperature is absolutely unacceptable.
Aspirin (Acetylsalicylic acid) - the use of the drug in children under 12 years of age for viral infections is prohibited due to the possible development of toxic encephalopathy with liver damage - Reye's syndrome.
Nimesulide (Nise, Nimulid) - several years ago was widely advertised as an antipyretic in children due to gaps in legislation. Reduces temperature remarkably. Produced only in India. In the civilized world, use in childhood is prohibited due to the possibility of developing severe liver damage (toxic hepatitis). At the moment, the use of the drug in children under 12 years of age in Russia is prohibited by the pharmaceutical committee.
✔5. It is forbidden!
— Applying cold objects to a child’s “feverish” body provokes a spasm of skin blood vessels. And if a decrease in skin temperature occurs, the temperature of the internal organs, on the contrary, increases, which poses an exceptional danger. — You can’t rub with alcohol or vinegar, because these substances enter the child’s body through the skin, which means poisoning is possible.
✔6. What to do if you have white fever?
If your child's skin, despite the high temperature, is pink and moist to the touch, you can be relatively calm - the balance between heat production and heat transfer is not disturbed. But if at a high temperature the skin is pale, the hands and feet are cold, and the child has chills, then this is “white fever”, in which vasospasm occurs. The cause may be damage to the central nervous system, lack of fluid, decreased blood pressure, and other reasons.
For white fever: 1) Try giving half a tablet of Nosh-pa and intensively rub the child’s cold limbs with your hands. Please note that antipyretics will not begin to act in full force until the vasospasm passes. Be sure to call an ambulance - they will inject the “lytic mixture”!
2) Eliminate any methods of physical cooling - rubbing, wrapping in cold sheets, etc.! Your child is already experiencing spasm of skin blood vessels.
✔7. Which form of medication should I choose?
When choosing the form of a medicine (liquid mixture, syrup, chewable tablets, suppositories), it should be taken into account that drugs in solution or syrup act in 20-30 minutes, in suppositories - in 30-45 minutes, but their effect is longer. Suppositories can be used in a situation where a child vomits when taking liquid or refuses to take medicine. It is better to use suppositories after the child has had a bowel movement; they are convenient to administer at night
, pediatrician, medical allergist
