Relief Advance ointment for external and rectal use 28.4g

Compound

Relief Advance ointment for external and rectal use 28.4g

Compound

Active substance: benzocaine - 200 mg (20%). Excipients: mineral oil (vaseline oil/liquid paraffin) - 120 mg (12%), petrolatum - 647 mg (64.7%), propylene glycol - 20 mg (2%), methyl parahydroxybenzoate - 2.4 mg (0.24%), propyl parahydroxybenzoate - 0.6 mg (0.06%), sorbitan monostearate - 10 mg (1%).

Pharmacokinetics

Data on the pharmacokinetics of the drug Relief® Advance are not provided.

Indications for use

As a local anesthetic:

• haemorrhoids;
• anal fissures;
• after proctological operations;
• during diagnostic procedures.

Contraindications

• thromboembolic disease;
• granulocytopenia;
• hypersensitivity to the components of the drug.

Directions for use and doses

The drug should be used after hygiene procedures.

Remove the protective cap from the applicator. Attach the applicator to the tube and squeeze out a small amount of ointment to lubricate the applicator. The ointment is carefully applied through the applicator to the affected areas outside or inside the anus up to 4 times a day in the morning, evening and after each bowel movement for 7-10 days.

After each use, rinse the applicator thoroughly and place it in the protective cap.

Children under 12 years of age: the drug should be used only on the recommendation of a doctor.

If there is no improvement after treatment, or symptoms worsen, or new symptoms appear, the patient should consult a doctor.

The drug should be used according to the indications, the method of administration and in the doses indicated in the instructions.

Storage conditions

The drug should be stored out of the reach of children at a temperature not exceeding 25°C.

Best before date

2 years. Do not use after expiration date.

special instructions

If there is heavy bleeding from the rectum or if painful symptoms persist for more than 7 days, you should additionally consult a proctologist.

There are reports that products containing benzocaine may cause methemoglobinemia. Symptoms such as cyanosis of the skin, lips and nails, headache, dizziness, shortness of breath (difficulty breathing), weakness, tachycardia, which are observed during treatment, may indicate potentially life-threatening methemoglobinemia, which requires immediate medical attention.

To minimize systemic side effects, do not exceed the recommended daily dose unless otherwise prescribed by a physician.

It is not recommended to use the drug on damaged skin, because this may increase systemic absorption.

Avoid contact of the drug with latex products (contraceptive diaphragms and condoms) to avoid reducing their effectiveness.

Description

Local anesthetic for use in proctology.

Dosage form

Ointment for rectal and external use is white with a yellowish tint, homogeneous, free of foreign inclusions.

Use in children

The question of prescribing Relief Advance for children under 12 years of age should be decided individually, depending on the clinical situation.

Action

Benzocaine has a local anesthetic effect and does not have a resorptive effect.

Side effects

The following adverse reactions have been reported with the use of benzocaine-containing products under various conditions. Since these reactions are listed in reference materials or are voluntarily reported in uncertain quantities from the population, it is not always possible to reliably estimate their frequency or establish a cause-and-effect relationship with the use of the drug.

From the immune system: allergic reactions.

From the blood and lymphatic system: methemoglobinemia.

From the skin and subcutaneous tissues: allergic dermatitis.

General and local reactions: erythema, local irritation, swelling, pain, rash at the site of application.

If the patient notices other side effects, the doctor should be informed.

Use during pregnancy and breastfeeding

The drug Relief® Advance is used during pregnancy and lactation (breastfeeding) with caution, in cases where the expected benefit to the mother outweighs the potential risk to the fetus or child.

Interaction

Drug interactions with Relief® Advance have not been described.

Overdose

Overdose symptoms may be related to the pharmacological effects of benzocaine. Its systemic absorption in case of overdose can be manifested by drowsiness, anxiety, agitation, and in severe cases - convulsions. Very rarely, the use of benzocaine in high doses can cause methemoglobinemia, which is manifested by respiratory distress and cyanosis.

Treatment: for methemoglobinemia - intravenous administration of methylene blue.

Impact on the ability to drive vehicles and operate machinery

Does not affect.

Directions for use and doses

Rectal suppositories

Rectally, after hygiene procedures.

Adults and children over 12 years of age: inject 1 supp into the rectum. up to 4 times a day (in the morning, at night and after each bowel movement).

Children under 12 years of age: Use as directed by a physician.

Ointment for rectal and external use

Externally, rectally, after hygiene procedures. Remove the protective cap from the applicator, attach the applicator to the tube and squeeze out a small amount of ointment to lubricate the applicator.

Apply the ointment carefully through the applicator to the affected areas outside or inside the anus up to 4 times a day in the morning, evening and after each bowel movement.

After each use, rinse the applicator thoroughly and place it in the protective cap.

Children under 12 years of age should only use it on the recommendation of a doctor.

Special instructions for the use of Relief Advance

In severe forms of hypertension, severe heart rhythm disturbances, severe thyrotoxicosis, and urinary disorders, the use of the drug must be agreed with a doctor. If thick bloody discharge from the anus appears or if painful symptoms persist for more than 7 days, you should additionally consult a doctor. Do not use the drug if the packaging is damaged or the protective plastic shell is missing. For children under 12 years of age, during pregnancy and breastfeeding, use the drug after consulting a doctor.

Relief® line preparations and their release forms

Effective treatment of hemorrhoids may require the use of local vasoconstrictors, analgesics and anti-inflammatory drugs. The drugs from the Relief line have the listed properties.

The manufacturer offers a whole line of products, which includes rectal suppositories and ointments. Certain types of the drug are prescribed for certain types of hemorrhoids. This form of drug release, such as rectal suppositories, is used mainly for the treatment of internal hemorrhoids, and ointment is used in the presence of not only internal, but also external manifestations of the disease.

Which Relief® should you choose?

Suppositories and ointments, in which the active ingredient is phenylephrine, are used by specialists to treat internal and external hemorrhoids, which are accompanied by bleeding and itching.

In the presence of severe pain and burning, both forms of the drug Relief Advance are used (rectal suppositories and ointment).

Which Relief is better for hemorrhoids accompanied by anal itching, eczema and dermatitis of the perianal area? In this case, you should choose anti-inflammatory rectal suppositories Relief Ultra.

Relief Advance, rectal suppositories, 12 pcs.

Manufacturer

Bayer Pharma AG, Germany

Compound

In 1 suppository:
benzocaine 206 mg.

Excipients:

cocoa bean butter - 1448 mg;

corn starch - 340 mg;

methyl parahydroxybenzoate - 2 mg;

propyl parahydroxybenzoate - 4 mg.

pharmachologic effect

Pharmacotherapeutic group: Local anesthetic ATC code: C05AD03 Pharmacodynamics: Benzocaine is a local anesthetic that does not have a resorptive effect. Cocoa butter has a softening effect.

Indications

Local anesthetic for hemorrhoids, anal fissures after proctological operations during diagnostic procedures.

Use during pregnancy and breastfeeding

The drug Relief Advance is used during pregnancy and lactation (breastfeeding) with caution and only if the expected benefit to the mother outweighs the potential risk to the fetus or child.

Contraindications

Hypersensitivity to the components of the drug - thromboembolic disease granulocytopenia.

Side effects

Local reactions (hyperemia) and allergic reactions are possible.

Interaction

Drug interactions with Relief Advance have not been described.

How to take, course of administration and dosage

The drug should be used after hygiene procedures. Adults and children over 12 years of age: insert 1 suppository into the rectum up to 4 times a day (in the morning at night and after each bowel movement). Children under 12 years of age: Use as directed by a physician.

Overdose

Overdose symptoms may be related to the pharmacological effects of benzocaine. Its systemic absorption in case of overdose can manifest itself as drowsiness, anxiety, agitation in severe cases - convulsions. Very rarely, large doses of benzocaine can cause methemoglobinemia, which is manifested by respiratory distress and cyanosis. Intravenous methylene blue is a specific treatment for this condition. If the recommended single and daily doses of shark liver oil are significantly exceeded, there may be a tendency to accelerate blood clotting.

Special instructions

It is not recommended to use the drug in children under 12 years of age without consulting a doctor. In case of accidental ingestion, you should immediately seek qualified help. If there is heavy bleeding from the anus or if painful symptoms persist for more than 7 days, you should consult a doctor.

Release form

Rectal suppositories

Storage conditions

In a dry place, protected from light, at room temperature no higher than 25 °C

Best before date

2 years

Active substance

Benzocaine

Dosage form

rectal suppositories

Purpose

For adults, Nursing mothers as prescribed by a doctor, Pregnant women as prescribed by a doctor, Children over 12 years old

Indications

Haemorrhoids

Barcode and weight

Barcode: 4250369503162 Weight: 0.038 kg

The difference between Relief® drugs

Let's take a closer look at how the candles in the Relief line differ from each other. The following rectal suppositories of this line are produced:

• Relief, the active ingredient of which is phenylephrine, which has a vasoconstrictor effect, which reduces swelling, itching and bleeding.
• Relief Advance is a local anesthetic used to treat local pain syndrome.
• Relief Ultra, the active ingredient in which is hydrocortisone acetate, an anti-inflammatory component used to treat itching and eczema of the anorectal area, and zinc sulfate, which is used to accelerate healing.

Now let's figure out what Relief ointments are. The manufacturer produces two types of the drug in this dosage form. The difference between them, as with rectal suppositories, lies in the composition and therapeutic effect.

There are such types of Relief ointments on sale as Relief ointment with phenylephrine, which has an anti-edematous and hemostatic effect. And also Relief Advance ointment, with benzocaine, which has an analgesic effect. Each of them has its own area of ​​application.