Heartburn. Each of us is familiar with an unpleasant burning sensation behind the sternum, in the esophagus, and sour belching. This phenomenon occurs due to the reflux of stomach contents into the esophagus. The main component of gastric juice is hydrochloric acid. It burns the mucous membranes and therefore heartburn occurs.
Acid reflux is not an independent disease. This is one of the symptoms of various inflammatory diseases of the gastrointestinal tract. It is necessary to treat the cause, but it is also desirable to remove unpleasant sensations during treatment. For this purpose, antacid drugs such as Rennie have been developed, we will find out the indications and contraindications.
Rennie's composition
One Rennie tablet contains: 680 mg calcium carbonate , 80 mg magnesium hydroxycarbonate .
Additional Ingredients: Pregelatinized corn starch, sucrose, potato starch, magnesium stearate, talc, liquid light paraffin, menthol flavor (gum arabic, maltodextrin, peppermint oil, silica), lemon flavor (maltodextrin, lemon oil, water) or peppermint flavor, or orange flavor.
Rennie drug overdose, symptoms and treatment
May be temporarily manifested by loose stools (liquid bowel movements). Long-term use of the drug in high doses can lead to the development of hypercalcemia, which disappears after stopping the drug. Long-term use of the drug in high doses by patients with impaired renal function can cause hypermagnesemia, hypercalcemia, alkalosis, which are manifested by nausea, vomiting, and muscle weakness. In case of overdose, the drug should be discontinued. Treatment is symptomatic. When used as recommended, overdose is unlikely.
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
Belongs to the group of antacid drugs. Includes magnesium carbonate and calcium carbonate , which provide rapid and long-term neutralization of excess hydrochloric acid in gastric juice. Has a protective effect on the gastric mucosa.
Achieving a therapeutic effect within three to five minutes is due to the rapid solubility of chewable tablets and the high calcium .
Pharmacokinetics
After interaction of the drug Rennie with gastric juice, magnesium and calcium . The degree of absorption of these salts depends on the dose of the drug used. The maximum degree of absorption is up to 20% magnesium and up to 10% calcium .
Small amounts of absorbed calcium and magnesium are excreted by the kidneys. In the intestines, insoluble substances are formed from soluble derivatives of the drug, which are excreted in feces.
Main active ingredient, release form and indications for use
Rennie is a white and creamy chewable tablet.
These are chewable tablets that are white with a creamy tint. They have a light menthol or orange scent.
For patients suffering from diabetes, an antacid is produced without the addition of any sugars. The main active ingredients are calcium carbonate and magnesium hydroxycarbonate.
The drug is packaged in cardboard blisters of 6 and 12 pieces per box. The main active ingredients of Rennie react with excess hydrochloric acid.
In this case, the latter is neutralized and the burning sensation goes away. The tablet begins to act 3-5 minutes after administration. Once in the stomach, the active ingredients form insoluble compounds. They and the remnants of the drug are excreted from the body with feces and urine. Indications for the drug:
- Heartburn, including in pregnant and lactating women
- Belching
- Feeling like your stomach is full
- Pain and heaviness in the stomach
- Various dyspeptic disorders associated with malnutrition
For more information about the drug Rennie, watch the video:
https://www.youtube.com/watch?v=C_9m2gZuZtE
Interaction
A decrease in the acidity of gastric juice due to the use of antacids leads to a decrease in the degree and rate of absorption of other drugs used simultaneously. Therefore, pharmaceutical drugs must be taken one and a half hours before or after taking Rennie.
When used together, antacids reduce the absorption of fluoroquinolones , tetracycline- type antibiotics, levothyroxine , cardiac glycosides, phosphates , iron preparations , and fluorides.
When used simultaneously with thiazide diuretics, it is recommended to regularly monitor the level of calcium in the blood.
Effective antacid dosages
Too much antacid may cause nausea.
According to the instructions, when symptoms of heartburn appear, children over 12 years of age and adult patients are recommended to take 1 or 2 chewable tablets.
The drug is not swallowed, but chewed thoroughly, and only then swallowed. If necessary, the next dose should be taken after 2 hours. Per day - no more than 16 tablets.
Overdose is possible only with long-term use of high doses of the drug. Excess antacid can cause the following pathologies:
- Hypercalcemia and hypermagnesemia
- Symptoms of alkalosis
- Nausea
- Vomit
- General weakness
If unpleasant signs appear, taking the drug "Rennie" should be discontinued.
Rennie's analogs
Level 4 ATC code matches:
Gastracid
Relzer
Maalox
Gaviscon Forte
Gastal
The most famous analogues of Rennie: Almagel, Alumag, Gastal, Maalox, Sekrepat Forte.
Rennie price, where to buy
Patients who have never used this remedy are interested in how much Rennie costs for heartburn in comparison with other antacid drugs. Market analysis shows that Rennie's price is an order of magnitude higher than the prices of its peers. Thus, the price of Rennie No. 12 tablets in Russia is 107-130 rubles. In Ukraine, the cost of Rennie No. 12, approved for use during pregnancy, can reach 40 hryvnia.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Rennie chewable tablets.
orange 24 pcs. Bayer Sante Familiale/Delpharm Gaillard RUR 347 order - Rennie chewable tablets. sugar-free mint 48 pcs. Bayer Sante Familiale/Delpharm Gaillard
RUR 559 order
- Rennie chewable tablets. menthol 12 pcs. Bayer Sante Familiale/Delpharm Gaillard
RUB 227 order
- Rennie chewable tablets. orange 48 pcs Delpharm Gaillard
RUR 559 order
- Rennie chewable tablets. sugar-free mint 24 pcs. Bayer Sante Familiale/Delpharm Gaillard
RUB 354 order
Pharmacy Dialogue
- Rennie chewable tablets No. 48 (orange) Delpharm Gaillard
RUR 552 order
- Rennie tablets No. 12 (menthol) Bayer
RUB 201 order
- Rennie tablets No. 12 (mint without sugar) Bayer
200 rub. order
- Rennie tablets No. 12 (orange) Bayer
RUB 204 order
- Rennie tablets No. 24 (orange) Bayer
RUB 333 order
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Pharmacy24
- Rennie mint N12 tablets Delpharm Gaillard, France
42 UAH. order - Rennie N12 orange tablets Delpharm Gaillard, France
46 UAH order
- Rennie menthol N12 tablets Delpharm Gaillard, France
42 UAH order
- Rennie N24 without sugar, mint tablets Delpharm Gaillard, France
82 UAH order
- Rennie N24 tablets Delpharm Gaillard, France
83 UAH order
PaniPharmacy
- Rennie tablets Rennie chewable tablets with menthol flavor No. 24 France, Delpharm Gaillard
93 UAH order
- Rennie sugar-free tablets Rennie sugar-free chewable mint tablets No. 24 France, Delpharm Gaillard
94 UAH order
- Rennie tablets Rennie chewable tablets with orange flavor No. 12 France, Delpharm Gaillard
53 UAH order
- Rennie tablets Rennie chewable tablets with orange flavor No. 24 France, Delpharm Gaillard
95 UAH order
- Rennie sugar-free tablets Rennie sugar-free chewable mint tablets No. 12 France, Delpharm Gaillard
52 UAH order
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Special instructions for the use of the drug Rennie
When prescribing the drug to persons with impaired renal function, the concentration of magnesium and calcium in the blood serum should be regularly monitored. The frequency of such examinations depends on the severity of renal failure and is determined individually. In such cases, you should refrain from long-term use of the drug in high doses. Warning for diabetics: Please note that 1 tablet of Rennie contains 475 mg of sucrose. Rennie sugar-free mint tablets contain saccharin and 400 mg of sorbitol and can be used by patients with diabetes. Taking Rennie in the recommended dose during pregnancy and breastfeeding does not pose any danger. The drug does not affect the ability to drive vehicles or operate machinery.
